NCT06028529Completed
Feasibility and Safety of a Portable Exoskeleton to Improve Mobility in Parkinson's Disease
Source: ClinicalTrials.gov · Last updated 7 Oct 2026
Brief summary (registry, in English)
Physical therapy approaches for balance and walking deficits in Parkinson's disease (PD) have limited effectiveness, with mostly short-lasting benefits. An exoskeleton is a device that straps to the legs and provides a passive force to assist people to better ambulate. The goal of this study is to establish the feasibility and safety of a lightweight exoskeleton on mobility and fall reduction in people with PD. As most PD patients eventually require assistive mobility devices, the exoskeleton represents a new option for increased, mobility, quality of life, and independence. Qualified subjects will come to the clinic twice weekly for eight weeks (16 total visits) and wear the exoskeleton device while walking under the supervision of a trained kinesiotherapist. Study staff will also interview participants and assess their PD symptoms, quality of life, and overall mobility. This study hopes to establish exoskeletons as modern, standard of care devices, which allow people with PD to maintain more independent and productive lives.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 10 (actual)
- First submitted
- 30 May 2023
- Start date
- 1 Sept 2024
- Primary completion date
- 25 Feb 2026
- Lead sponsor
- VA Office of Research and Development
- Diseases
- Parkinson disease
- NCT number
- NCT06028529
What you commit to
- Study type: Interventional
- Participants enrolled: 10
- From 1 Sept 2024 to the primary completion date, 25 Feb 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Neurological, musculoskeletal, or other disorders unrelated to PD contributing to impairment of stance, gait, balance or coordination
- Severe congestive heart failure (CHF), chronic obstructive pulmonary disease (COPD), or those requiring nasal canula O2
- History of implantable cardiac device or ablative surgery
- Moderately-severe to severe cognitive impairment / dementia (Montreal Cognitive Assessment \< 17/30)
- Failure to meet B-Temia-established hip and knee flexion and extension manual muscle test (MMT) prerequisite screening parameters, which assure that individuals can adequately engage and walk against the resistive forces of the Keeogo
Other
- Symptomatic orthostatic hypotension with exertion
- Feeding tube or associated port placement (PEG/J-PEG)
- Body height less than 5'1" or greater than 6'3"
- Body weight greater than 250 pounds
- Amputation of any portion of the lower limbs
- Osteoporosis as defined by DEXA Scan T score \< -2.5
- Inability to complete 20 minutes of walking with the exoskeleton (over a maximum period of one hour) at the initial screening/testing session
Who the study is looking for
- Parkinson's disease (PD) confirmed by a Parkinson's Disease Research, Education and Clinical Center (PADRECC) movement disorder specialist using UK Brain Bank Criteria
- Modified Hoehn and Yahr (H\&Y) stage II-V
- Veteran
- Able to attend visits at the Richmond VA Medical Center
Age in the registry: 18 years to 90 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Richmond VA Medical Center, Richmond, VA Coordinator of this site? Confirm its status | Richmond | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.