NCT06029452Completed
A Retrospective Validation Study To Identify Chart-Based Clinical Diagnosis Of Wild-Type Transthyretin Amyloid Cardiomyopathy (Attrwt-CM) And Non-Amyloid Heart Failure Among Patients With Heart Failure (HF).
A Retrospective Chart Validation Study Evaluating the Performance of Machine Learning Algorithm (ML) to Predict the Clinical Diagnosis of Wild-type Transthyretin Amyloid Cardiomyopathy (ATTRwt-CM) and Non-amyloid Heart Failure Among Patients With Heart Failure (HF)
Source: ClinicalTrials.gov · Last updated 3 Jan 2025
Brief summary (registry, in English)
This is an observational, retrospective non-inferiority study with a study sample from a large national database. A machine learning (ML) model will use a national database to predict the clinical diagnosis of ATTRwt-CM among HF patients. This study will include HF patients ≥50 years old.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 558 (actual)
- First submitted
- 1 Sept 2023
- Start date
- 1 Sept 2023
- Primary completion date
- 14 Nov 2023
- Lead sponsor
- Pfizer
- Diseases
- Amyloidosis, Heart failure
- NCT number
- NCT06029452
What you commit to
- Study type: Observational
- Participants enrolled: 558
- From 1 Sept 2023 to the primary completion date, 14 Nov 2023
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Patients with any of the following diagnoses:
- Light chain (AL) amyloidosis
- Intracranial hemorrhage
- Cerebral amyloid angiopathy
- End stage renal disease
- Blood cancer
Who the study is looking for
- HF patients (defined as having ≥1 claim for HF or HF treatment) ≥50 years old with clinical diagnosis of ATTRwt-CM or non-amyloid HF ascertained by charts. Patients will be required to have ≥12 months of continuous activity in the EHR or claims prior to the Index Date.
Age in the registry: 50 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Pfizer Coordinator of this site? Confirm its status | New York | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.