NCT06030752Recruiting
WMT for Autism Spectrum Disorder (ASD)
Washed Microbiota Transplantation (WMT) for Autism Spectrum Disorder (ASD)
Source: ClinicalTrials.gov · Last updated 18 Sept 2026
Brief summary (registry, in English)
Autism Spectrum Disorder (ASD) is a group of serious neurodevelopmental disorders. A significant comorbidity exists between ADHD and ASD: 30%-50% of individuals with ASD exhibit ADHD symptoms, and two-thirds with ADHD show ASD traits. Intestinal microbial disturbance is common in children with ASD. A great deal of evidence shows that intestinal microbes can influence the brain to play its role through "gut-brain-microbiota axis". We intend to explore the role of Washed Microbiota Transplantation in improving symptoms of children in ASD with or without ADHD; To study the potential etiological mechanism of WMT for the neurodevelopmental disorders.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 80 (estimated)
- First submitted
- 25 May 2023
- Start date
- 20 Sept 2023
- Primary completion date
- 4 Apr 2027
- Lead sponsor
- The Second Hospital of Nanjing Medical University
- Diseases
- Autism
- NCT number
- NCT06030752
What you commit to
- Study type: Observational
- Planned participants: 80
- From 20 Sept 2023 to the primary completion date, 4 Apr 2027
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Diagnosed with a single-gene disorder, major brain malformations, gastrointestinal diseases (ulcerative colitis, Crohn's disease, or eosinophilic esophagitis)
- Had severe comorbidities including cardiopulmonary failure, severe liver, and kidney diseases, severe infection, tumors, etc.
- Accompanied with other life-threatening disorders required emergency treatment.
Other
- Their guardian could not understand the questionnaires or provide informed consent.
- Unable to tolerate colonoscopy or anesthesia.
Who the study is looking for
- Children and adolescents with an established diagnosis of ASD or ADHD + ASD according to the Diagnostic and Statistical Manual Of Mental Disorders Fifth Edition;.
- Age 3-17 years.
- Received stable treatments for ≥1 month preceding WMT
Age in the registry: 3 years to 17 years · Sex: All · Does not accept healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Sir Run Run Hospital of Nanjing Medical University Coordinator of this site? Confirm its status | Nanjing | China | Recruiting |
| Department of Microbiota Medicine & Medical Centre for Digestive Diseases, The Second Affiliated Hospital of Nanjing Medical University Coordinator of this site? Confirm its status | Nanjing | China | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.