NCT06038643Completed
Intergenerational Behavioral Intervention to Enhance Physical Activity in Older Adults at Risk for Alzheimer's Disease
The Healthy Aging Brain Study: A Remote Behavioral Intervention to Enhance Physical Activity in Older Adults.
Source: ClinicalTrials.gov · Last updated 9 Jul 2025
Brief summary (registry, in English)
This is a four-week pilot randomized controlled trial of a behavioral intervention in older adults at risk for Alzheimer's disease. Older participants are a subgroup from the PREVENT-AD longitudinal cohort. We will test whether a four-week intergenerational social motivation using a technology-based platform (intervention group) enhances physical activity relative to a control group.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 76 (actual)
- First submitted
- 25 Apr 2022
- Start date
- 8 Oct 2023
- Primary completion date
- 14 Apr 2024
- Lead sponsor
- Douglas Mental Health University Institute
- Diseases
- Alzheimer disease
- NCT number
- NCT06038643
What you commit to
- Study type: Interventional
- Participants enrolled: 76
- From 8 Oct 2023 to the primary completion date, 14 Apr 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Criteria the registry did not label
- Main Participant Inclusion criteria:
- Men and women \> 60 years Who are current participants of the PREVENT-AD Longitudinal Cohort at McGill University.
- No contraindications to MRI Imaging. Normal cognition Not exercising more than 150 minutes of moderate-intensity exercise per week or sitting more than 8 hours per day AND responded "yes" to the question "Do you want to increase your physical activity?" Fluency in English or French Access to a computer or smartphone with internet Normal or corrected-to-normal vision based on the minimal 20/20 standard Ambulatory without significant increase in pain with walking or the assistance of walking devices
- Main Participant Exclusion Criteria:
- Primary care physician does not approve additional physical activity An inability to ambulate without the assistance of another person or severe pain
- Any unstable medical condition:
- History of a psychiatric illness including schizophrenia or Attention Deficit Hyperactivity Disorder (ADHD). History of anxiety or depression accepted if stable on medication for at least 6 months
- Current treatment for cancer - except non-melanoma skin cancer
- Neurological condition (e.g., multiple sclerosis, Parkinson's disease, and stroke)
- Current alcohol or substance abuse
- Current treatment for congestive heart failure, angina, uncontrolled arrhythmia, Deep Venous Thrombosis (DVT) or other unstable cardiovascular condition
- Myocardial infarction, coronary artery bypass grafting, angioplasty or other cardiac event in the past six months.
- Younger Adult Inclusion Criteria:
- Can be identified as child or grandchild of participant (biological or adopted), 14 years or older.
- Can be a young adult (18 years or older) who is not a relative of the main participant, in case a grandchild or child is not available.
- Stable on antidepressants for more than 6 months.
- In contact with the primary participant more than once per 12 months at baseline
- Lives anywhere in Canada if 18 years and older, or anywhere accessible by mail in Quebec if 14 years and older but younger than 18 years.
- Normal or corrected-to-normal vision based on the minimal 20/20 standard to complete the cognitive tasks
- Able to speak, read, and write English or French
- No diagnosis of neurological disease or unstable health condition
- Study Partner Exclusion Criteria:
- Not in contact with the primary participant more than once per 12 months at baseline
Age in the registry: 60 years to 95 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Douglas Mental Health University Institute Coordinator of this site? Confirm its status | Montreal | Canada | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.