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NCT06039267Completed

Brain Health & the Microbiome

Brain Health & the Microbiome: A Proof-of-Concept Study in Patients With Mild Cognitive Impairment

Source: ClinicalTrials.gov · Last updated 29 Jan 2026

Brief summary (registry, in English)

The GW SMHS supports research in complementary and integrative approaches to treatment of sickness and disease and for health promotion. Sometimes, research may involve asking questions of patients, students, and health providers. In this study, individuals are being asked to participate in this study as either 1) a healthy volunteer, 2) a person with Mild Cognitive Impairment (MCI), or 3) a person with early Alzheimer's disease (eAD). We are trying to learn more about if the gut microbiome (the microbes that live in our digestive tract) of individuals with eAD, MCI, and healthy controls are altered following lifestyle changes. This research will provide the pilot data to begin to understand if these changes in the gut microbiome are beneficial to health and/or may slow or halt the progression of MCI or early Alzheimer's.

Status (registry)
Completed
Study type
Observational
Enrollment
44 (actual)
First submitted
31 Aug 2023
Start date
25 Aug 2023
Primary completion date
24 Aug 2025
Lead sponsor
George Washington University
NCT number
NCT06039267

What you commit to

  • Study type: Observational
  • Participants enrolled: 44
  • From 25 Aug 2023 to the primary completion date, 24 Aug 2025
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other

  • Criteria or pathology that may affect the outcomes of the study or the risk/benefit ratio as determined by the study team

Who the study is looking for

  • Age 50-90
  • Early Alzheimer's Disease (eAD)
  • Mild Cognitive Impairment (MCI)
  • Healthy Control (no eAD or MCI)

Age in the registry: 50 years to 90 years · Sex: All · Accepts healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
George Washington University School of Medicine & Health Sciences
Coordinator of this site? Confirm its status
Washington D.C.United StatesUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.