NCT06039787Recruiting
Exercise Training on Brain Insulin Responsiveness
Effects of One Exercise Training Session on Brain Insulin Responsiveness
Source: ClinicalTrials.gov · Last updated 8 Nov 2023 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
The overarching goal of the current study is to investigate the effect of one acute bout of exercise on the brain insulin responsiveness in a cross-over study design. To this end, investigators will compare the effect of two single endurance exercise sessions with different intensities, namely moderate intensity continuous training (MICT) and high-intensity-interval-training (HIIT), which will be performed in a randomized order. This will be compared to a waiting control condition.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 40 (estimated)
- First submitted
- 6 Sept 2023
- Start date
- 20 Oct 2023
- Primary completion date
- 31 Dec 2026
- Lead sponsor
- University Hospital Tuebingen
- Diseases
- Obesity
- NCT number
- NCT06039787
What you commit to
- Study type: Interventional
- Planned participants: 40
- From 20 Oct 2023 to the primary completion date, 31 Dec 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Taking psychotropic drugs
- Regular use of analgesic drugs
- Previous bariatric surgery
Other illness
- Type 2 diabetes, cardiovascular diseases such as chronic heart failure, myocardial infarction, status post stroke
- Limitations to participate in ergometer-based exercise (balance and coordination disorders, orthopedic problems, …)
- History of severe mental or somatic disorders including neurological diseases (incl. epileptic seizures and migraines)
- Acute infection within the last 4 weeks
- Other diseases that in the opinion of the investigator may jeopardize the success of the study or indicate a risk to the volunteer
- Metal implants which cannot be removed as pacemakers, artificial heart valve, electrical devices as insulin pumps, large tattoos, retainer over more than 4 teeth, contraceptive coil, implanted magnetic metal parts as screws or plates after a surgery
Lab values
- Taking medications that influence glucose metabolism
- Hemoglobin values less than 12g/dl for women, less than 14 g/dl for men
Other
- Insufficient knowledge of the German language
- Persons who cannot legally give consent
- Pregnancy or lactation
- Taking anticoagulant agents
- Current participation in a lifestyle intervention study or a pharmaceutical study
- Persons with claustrophobia
- Temperature-sensitive person
- Persons with tinnitus or increased sensitivity to loud sounds
Who the study is looking for
- BMI between ≥ 19.5 to 39 kg/m2-
- Less than 150 min/week for moderate-intensity physical activity
- Less than 75 min/week for Vigorous- intensity exercise (WHO recommendations for regular physical activity of adults)
- Written consent to participate in the study
- Written consent to be informed about incidental findings
Age in the registry: 20 years to 65 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University Clinic Tübingen, Department of Internal Medicine IV Coordinator of this site? Confirm its status | Tübingen | Germany | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.