NCT06040905Completed
Causal Effect of Coenzyme Q10 Nutrition and Cognitive Dysfunction in the Metabolic Storm (Hyperglycemia and Sarcopenia) and Brain-derived Neurotrophic Factor
Source: ClinicalTrials.gov · Last updated 21 Aug 2026
Brief summary (registry, in English)
The aim of the study is to investigate the effects of coenzyme Q10 supplementation (150 mg twice daily; 300 mg/day for 12 weeks) on coenzyme Q10 status, glucose parameters, BDNF, myokines, and cognitive function in patients with mild cognitive impairment (MCI) or Alzheimer's disease (AD) and hyperglycemia, either without sarcopenia risk or with pre-sarcopenia/sarcopenia risk.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 51 (actual)
- First submitted
- 4 Sept 2023
- Start date
- 24 Jan 2024
- Primary completion date
- 12 Feb 2026
- Lead sponsor
- Chung Shan Medical University
- Diseases
- Alzheimer disease
- NCT number
- NCT06040905
What you commit to
- Study type: Interventional
- Participants enrolled: 51
- From 24 Jan 2024 to the primary completion date, 12 Feb 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Current warfarin therapy.
Other illness
- Cancer.
- Severe cardiac, pulmonary, hepatic, or renal disease.
Other
- Severe disability or aphasia.
- Malnutrition (body weight change \>5% within one month).
- Current use of coenzyme Q10 supplements.
Who the study is looking for
- Clinical diagnosis of mild cognitive impairment (MCI) or Alzheimer's disease (AD).
- Hyperglycemia, defined as fasting plasma glucose ≥100 mg/dL or current use of glucose-lowering medication.
- Either without sarcopenia risk or with pre-sarcopenia/sarcopenia risk, as determined by calf circumference, handgrip strength, or muscle endurance.
- Ability to swallow tablets.
Age in the registry: 50 years to 80 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Chung Shan Medical University Hospital Coordinator of this site? Confirm its status | Taichung | Taiwan | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.