NCT06041529Active, not recruitingPhase 4
Study to Evaluate the Efficacy and Safety of TEL/AML/CTD in Elderly Patients With Essential Hypertension
An Open-Label, Superiority, Randomized, Comparative Study to Evaluate the Efficacy and Safety of Telmisartan, Amlodipine, and Chlorthalidone Fixed-Dose Combination Versus Telmisartan, Amlodipine, and Hydrochlorothiazide in Elderly Patients With Essential Hypertension Uncontrolled by Telmisartan and Amlodipine Combinations
Source: ClinicalTrials.gov · Last updated 13 Feb 2026
Brief summary (registry, in English)
This study is to compare the efficacy and safety of Telmisartan, Amlodipine, and Chlorthalidone Fixed-Dose Combination and Telmisartan, Amlodipine, and Hydrochlorothiazide in Elderly Patients with Essential Hypertension Uncontrolled by Telmisartan and Amlodipine Combinations
- Status (registry)
- Active, not recruiting
- Phase (registry)
- Phase 4
- Study type
- Interventional
- Enrollment
- 198 (actual)
- First submitted
- 4 Sept 2023
- Start date
- 18 Oct 2023
- Primary completion date
- 28 Feb 2026
- Lead sponsor
- Yuhan Corporation
- Diseases
- High blood pressure
- NCT number
- NCT06041529
What you commit to
- Study type: Interventional · Phase 4
- Participants enrolled: 198
- From 18 Oct 2023 to the primary completion date, 28 Feb 2026
- 15 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Known hypersensitivity to components of the investigational product
- Patient who is unable to stop taking prohibited drugs
- Administration of other investigational products within 3 months prior to screening.
Other illness
- Patient who has history of drug allergic reactions
Other
- Test results showing the following values at screening
- The change of MSSBP ≥ 20 mmHg and MSDBP ≥ 10 mmHg on target arm between 1st and 2nd measurements
- Pregnant or lactating women
- Patient who is unable to maintain proper night sleep
- Malnutrition, starvation, debilitating factors, A person who is being forcibly detained for the treatment of mental or physical
- An impossible one who participates in clinical trial by investigator's decision
Who the study is looking for
- Participants who have been fully informed about the purpose, content, and characteristics of investigational product, and have voluntarily agreed in writing
- Aged ≥ 65 with essential hypertension
- Patient with uncontrolled essential hypertension at screening
- If already taking antihypertensive drugs, mean sitting systolic blood pressure (MSSBP) must be 140 mmHg ≤ MSSBP \< 200 mmHg
- If not taking any antihypertensive drugs at least 4 weeks, mean sitting systolic blood pressure (MSSBP) must be 160 mmHg ≤ MSSBP \< 200 mmHg
Age in the registry: 65 years to - · Sex: All · Does not accept healthy volunteers
Sites (15)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Pusan National University Yangsan Hospital Coordinator of this site? Confirm its status | Busan | South Korea | Unknown status |
| The Catholic University of Korea, Daejeon ST.Mary's Hospital Coordinator of this site? Confirm its status | Daejeon | South Korea | Unknown status |
| Chonnam National University Hospital Coordinator of this site? Confirm its status | Gwangju | South Korea | Unknown status |
| Gwangju Veterans Hospital Coordinator of this site? Confirm its status | Gwangju | South Korea | Unknown status |
| The Catholic University of Korea St. Vincent's Hospital Coordinator of this site? Confirm its status | Gyeonggi-do | South Korea | Unknown status |
| The Catholic University of Korea, Incheon St. Mary's Hospital Coordinator of this site? Confirm its status | Incheon | South Korea | Unknown status |
| Seoul national University Budang hospital Coordinator of this site? Confirm its status | Seoul | South Korea | Unknown status |
| Korea University Guro Hospital Coordinator of this site? Confirm its status | Seoul | South Korea | Unknown status |
| The Catholic University of Korea, Uijeongbu ST. Mary's Hospital Coordinator of this site? Confirm its status | Seoul | South Korea | Unknown status |
| The Catholic University of Korea Bucheon St.Mary's Hospital Coordinator of this site? Confirm its status | Seoul | South Korea | Unknown status |
| The Catholic University of Korea, Eunpyeong St. Mary's Hospital Coordinator of this site? Confirm its status | Seoul | South Korea | Unknown status |
| The Catholic University of Korea Yeouido St. Mary's Hospital Coordinator of this site? Confirm its status | Seoul | South Korea | Unknown status |
| Hanyang University Medical Center Coordinator of this site? Confirm its status | Seoul | South Korea | Unknown status |
| The Catholic University of Korea, Seoul ST. Mary's Hospital Coordinator of this site? Confirm its status | Seoul | South Korea | Unknown status |
| Wonju Severance Christian Hospital Coordinator of this site? Confirm its status | Wŏnju | South Korea | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.