NCT06042439Recruiting
AM vs PM Exercise Training
Effects of AM vs. PM Exercise Training on Blood Pressure and Vascular Health in Postmenopausal Females With Hypertension
Source: ClinicalTrials.gov · Last updated 1 Oct 2026
Brief summary (registry, in English)
The treatment of high blood pressure, or hypertension, is multifaceted and can include pharmacological therapies (i.e., medications) and lifestyle modifications such as physical activity. Chronotherapy, which describes timing of a treatment with the body's daily rhythms, has recently been used with hypertension medications and has been shown to be effective at lowering blood pressure and reducing the risk of cardiovascular disease events. Specifically, taking medications in the evening was shown to be more effective than morning medication routines. Little information is available about the effectiveness of chronotherapy combined with exercise (i.e., planned physical activity) interventions in older adults with hypertension. The purpose of this study is to examine how exercise training performed in the morning and early evening affects blood pressure and other measures of blood vessel health in postmenopausal females with hypertension.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 79 (estimated)
- First submitted
- 6 Sept 2023
- Start date
- 11 Jun 2024
- Primary completion date
- 1 Jul 2027
- Lead sponsor
- Michigan State University
- Diseases
- High blood pressure
- NCT number
- NCT06042439
What you commit to
- Study type: Interventional
- Planned participants: 79
- From 11 Jun 2024 to the primary completion date, 1 Jul 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Overt pulmonary disease/condition as follows: chronic bronchitis, chronic obstructive pulmonary disease, emphysema, or pulmonary hypertension
- Cardiometabolic disease/condition as follows: diabetes, heart failure, peripheral arterial disease, stroke, coronary artery disease, renal disease, secondary hypertension, chronic venous insufficiency or deep vein thrombosis within last 6 months
- Cancer within last 5 years
- uncontrolled thyroid disorder
- Parkinson's disease
- Dementia
- Unstable angina
Other
- Habitually physically active defined as 150 minutes of moderate-intensity or 75 minutes of vigorous-intensity aerobic physical activity per week
- Body mass index \>39 kg/m2
- Current smoking or vape
- Evening shift work
- 2 or more falls in the last year
- Anemia within 3 months of enrollment
- Acute pulmonary embolus or infarction
- Acute myocarditis or pericarditis
- Acute aortic dissection
Who the study is looking for
- Systolic BP equal to or greater than 130 mmHg without BP medication or greater than 120 mmHg with medication and diastolic blood pressure equal to and greater than 80 mmHg
- 55-80 years old
- Post-menopausal female
- Able to walk without assistance
Age in the registry: 55 years to 80 years · Sex: Female · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Michigan State University Coordinator of this site? Confirm its status | East Lansing | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.