NCT06042751Completed
Psychosomatic, Physical Activity or Both for Post-covid19 Syndrom
Randomized Comparison of a Telemedicine-supported Psychosomatic Intervention, a Physical Activity Intervention and the Combination of Both in Patients With Post-covid19 Syndrom.
Source: ClinicalTrials.gov · Last updated 17 Aug 2026
Brief summary (registry, in English)
Post-Covid(PoC)-patients with fatigue symptoms respond very differently to physical rehabilitation programs. While PoC-patients with psychological symptoms benefit little from physical interventions, fatigue and exercise capacity improves significantly without the presence of psychological symptoms. RCT studies on effects of psychotherapy or the combination of phsical activity with psychotherapy in PoC are not yet available. Therefore, the aim is to investigate the unimodal effects of psychotherapy and exercise therapy or the combination of both on fatigue in PoC patients with fatigue in a randomized clinical trial. Patients will be assigned to the three intervention groups (psychotherapy, physical rehabilitation, combination of both) stratified for sex, gender and BMI status. The intervention duration is 3 months with therapeutic online sessions for 50 min every 2 weeks. After another 3 months without intervention, the sustainability will evaluated. Secondarily, the investigators analyzes which patient benefits most from which therapeutic approach and seek for specific predictors of patient´s individual response.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 195 (actual)
- First submitted
- 5 Sept 2023
- Start date
- 1 Jan 2024
- Primary completion date
- 10 May 2026
- Lead sponsor
- Hannover Medical School
- Diseases
- Long COVID and ME/CFS
- NCT number
- NCT06042751
What you commit to
- Study type: Interventional
- Participants enrolled: 195
- From 1 Jan 2024 to the primary completion date, 10 May 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Illnesses or functional disorders that potentially explain the fatigue symptoms otherwise
- Any illness or impairment that the examining physician judges to preclude participation in a physical training intervention
- Suicidality or severe mental illness (e.g. mania, acute phase of schizophrenia) that requires acute treatment.
Other
- Current participation in another intervention study
Who the study is looking for
- Patients aged over 18 and
- diagnosed post-Covid-19 syndrome: (positive PCR or antibody test) and Fatigue Assessment Scale (FAS) ≥ 22 points
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Hannover Medical School Coordinator of this site? Confirm its status | Hanover | Germany | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.