NCT06044792Not yet recruiting
The Influence of Primary HIV-1 Drug Resistance Mutations on Immune Reconstruction in PLWH
The Influence of Primary HIV-1 Drug Resistance Mutations on Immune Reconstruction in Patients Treated With Antiretroviral Drugs - an Observational Cohort Study.
Source: ClinicalTrials.gov · Last updated 21 Sept 2023 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
Since the reasons for differential immune reconstitution in HIV-infected patients are still not fully understood, we considered it reasonable to investigate whether the presence of primary HIV drug resistance mutations could be one of the factors of inadequate immune reconstitution. Evaluation of unfavorable factors of immune reconstitution can help identify patients at risk of persistently low CD4 cell counts and CD4:CD8 ratios and requiring careful monitoring for progression to AIDS.
- Status (registry)
- Not yet recruiting
- Study type
- Observational
- Enrollment
- 50 (estimated)
- First submitted
- 3 Sept 2023
- Start date
- Sept 2023
- Primary completion date
- Sept 2027
- Lead sponsor
- Medical University of Warsaw
- Diseases
- HIV
- NCT number
- NCT06044792
What you commit to
- Study type: Observational
- Planned participants: 50
- From Sept 2023 to the primary completion date, Sept 2027
- No sites listed in no country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- use of chemotherapy, immunosuppressive drugs and other myelotoxic agents
Other
- hematologic neoplasms
- lack of patient's consent to participate in the study
Who the study is looking for
- HIV-1 confirmed infection
- ART naive patients \> 18 years
- virological suppression after 6 months of ART
- available results of HIV genotyping before the start of ART
Age in the registry: 18 years to 100 years · Sex: All
This page is information, not medical advice. Discuss any trial with your doctor.