NCT06045195Not yet recruitingPhase 2
Pembrolizumab in First-Line Treatment of Advanced-Stage Classical Hodgkin Lymphoma
Phase II Trial of Pembrolizumab in First-Line Treatment of Advanced-Stage Classical Hodgkin Lymphoma
Source: ClinicalTrials.gov · Last updated 6 Apr 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
The primary objective of this trial is to estimate efficacy of the novel regimen. The primary endpoint is the 1-year PFS rate after treatment with one dose of pembrolizumab followed by four to six cycles of chemo-immunotherapy with P-BrECADD, and PET-guided radiotherapy as per standard of care
- Status (registry)
- Not yet recruiting
- Phase (registry)
- Phase 2
- Study type
- Interventional
- Enrollment
- 40 (estimated)
- First submitted
- 12 Sept 2023
- Start date
- Aug 2025
- Primary completion date
- Jan 2027
- Lead sponsor
- University of Cologne
- Diseases
- Hodgkin lymphoma
- NCT number
- NCT06045195
What you commit to
- Study type: Interventional · Phase 2
- Planned participants: 40
- From Aug 2025 to the primary completion date, Jan 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Criteria the registry did not label
- Main Inclusion Criteria:
- age 18-60
- advanced stage classical Hodgkin Lymphoma
- no previous treatment for cHL
- Main Exclusion Criteria:
- Nodular lymphocyte-predominant Hodgkin lymphoma or composite lymphoma
- Chemotherapy or radiotherapy in medical history
- Prior or concurrent disease that prevents treatment according to protocol
Age in the registry: 18 years to 60 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| 1st Department of Medicine, Cologne University Hospital Coordinator of this site? Confirm its status | Cologne | Germany | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.