NCT06051136Active, not recruiting
Early Versus Delayed Rehabilitation Intervention in Patients With Lung Cancer
Feasibility of an Early Versus Delayed Rehabilitation Intervention in Patients With Lung Cancer on Cancer-related Fatigue: a Pilot RCT
Source: ClinicalTrials.gov · Last updated 7 May 2026
Brief summary (registry, in English)
In Italy, the incidence of lung cancer for the year 2020 has been estimated at about 41.000 new diagnoses. Patients with lung cancer experience debilitating symptoms caused by the disease itself and cancer treatments, such as dyspnea and fatigue, which reduce physical function and quality of life (QoL). It is estimated that 90% of patients undergoing chemotherapy and 57% of patients undergoing lung resection suffer of Cancer-Related Fatigue (CRF). Previous studies have shown that educational interventions and aerobic and resistance exercise are effective in improving CRF and QoL in patients with lung cancer. However, to date the optimal dose, mode and timing to deliver the intervention during the care pathway for lung cancer patients is unknown. Tolerability and frequency of cancer treatment could be a barrier to adherence to the intervention. Therefore, this study aims to evaluate the feasibility of a rehabilitation intervention aimed at improving CRF with respect to timing of delivery: early vs delayed rehabilitation in lung cancer patients.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 31 (actual)
- First submitted
- 17 Sept 2023
- Start date
- 10 Mar 2023
- Primary completion date
- 23 Dec 2024
- Lead sponsor
- Azienda USL Reggio Emilia - IRCCS
- Diseases
- Lung cancer
- NCT number
- NCT06051136
What you commit to
- Study type: Interventional
- Participants enrolled: 31
- From 10 Mar 2023 to the primary completion date, 23 Dec 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patients who are candidates for surgery alone
- Patients who are candidates for neoadjuvant therapy
Other illness
- Clinical disorders that contraindicate participation in a moderate exercise program (e.g. preexisting severe physical disabilities, major cognitive or sensory deficits, severe psychiatric disorders, language barrier, etc.).
Other
- NSCLC stage IV
Who the study is looking for
- Newly diagnosed of stage II and III lung cancer (NSCLC) candidates for anticancer therapies (chemotherapy, radiotherapy, immunotherapy, or combinations thereof), associated or not with surgery. In the last case, patients will be included at least 30 days after surgery.
- Prognosis ≥ 12 months
- At least 18 years old
- Recruited from the pneumology, oncology, radiotherapy, and physical medicine and rehabilitation unit of the Azienda Unità Sanitaria Locale - IRCCS of Reggio Emilia
- Willing and able to give written informed consent
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Azienda Unità Sanitaria Locale - IRCCS di Reggio Emilia Coordinator of this site? Confirm its status | Reggio Emilia | Italy | Unknown status |
Related publications
- Feasibility of an early versus delayed rehabilitation intervention in patients with lung cancer on cancer-related fatigue: a pilot RCT.Future Oncol · 2026 · PMID 41496492
This page is information, not medical advice. Discuss any trial with your doctor.