NCT06054360Recruiting
Predictive Value of Right Atrial Strain in Postoperative Atrial Fibrillation in Patients Undergoing Cardiac Surgery
Source: ClinicalTrials.gov · Last updated 28 May 2026
Brief summary (registry, in English)
The incidence of postoperative atrial fibrillation (POAF) after cardiac surgery is around 30%. POAF increases the risk of developing permanent atrial fibrillation and raises the risk of cardiac decompensation, stroke, acute myocardial infarction, and death. While the role of the left atrium (LAF) in the pathophysiology of POAF is now well-established, the part of the right atrium (RA) remains poorly understood. Recent studies suggest a correlation between RA function and POAF. RA function can be assessed by transthoracic echocardiography (TTE) with dedicated software for measuring the RA strain (RAS). RA function is thus divided into three phases: reservoir (RASr), conduit, and contraction. Numerous studies have demonstrated that a significant alteration in RAS predicts POAF in various clinical contexts. Therefore, it is essential to investigate whether alterations in RA function assessed by 2D-STE (RAS) are associated with an increased occurrence of FAPO after cardiac surgery. It is essential to investigate whether alterations in RA function assessed by 2D-STE (RAS) are associated with an increased occurrence of FAPO after cardiac surgery.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 334 (estimated)
- First submitted
- 19 Sept 2023
- Start date
- 9 Oct 2023
- Primary completion date
- 9 Oct 2026
- Lead sponsor
- Centre Hospitalier Universitaire, Amiens
- Diseases
- Atrial fibrillation
- NCT number
- NCT06054360
What you commit to
- Study type: Observational
- Planned participants: 334
- From 9 Oct 2023 to the primary completion date, 9 Oct 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patient receiving circulatory mechanical assistance before surgery.
Other illness
- History of atrial fibrillation or flutter.
- Valvular and ascending aorta cardiac surgery
- Urgent cardiac surgery.
- Presence of tricuspid insufficiency greater than grade 2.
- Dependency on ventricular and atrial pacing by an internal or external cardiac pacemaker during the echocardiographic examination.
Lab values
- Left ventricular ejection fraction lower than 50%.
Other
- Patients participating in an interventional study may modify the incidence of POAF.
Who the study is looking for
- Adult patient (\>18 years old)
- The patient was hospitalized at the Amiens University Hospital for scheduled aortocoronary bypass grafting under cardiopulmonary bypass.
- Echocardiographic image quality enabling the measurement of RAS parameters
- Patient affiliation to a social security scheme
- Patient/proxy information and collection of their non-opposition.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Chu Amiens Picardie Coordinator of this site? Confirm its status | Amiens | France | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.