NCT06058598Active, not recruiting
Exercise Training in Patients With Glaucoma
High Intensity Interval Training in Patients With Glaucoma
Source: ClinicalTrials.gov · Last updated 17 Dec 2025
Brief summary (registry, in English)
HIT GLAUCOMA is a multicenter exercise study for glaucoma patients between three institutes: the Department of Sport, Exercise and Health (DSBG) of the University of Basel, the Eye Clinic at the University Hospital Basel and the UZ Leuven (Belgium). The main objective of the study is to investigate the possibility of using exercise therapy to treat glaucoma. Participants will be randomly divided into two groups: Intervention and Control group. The intervention group will receive a high-intensity interval training plan, and the control group will receive lifestyle counseling and standard therapy. With this method, the study aims to validate an exercise therapy concept that could significantly improve disease progression and quality of life in patients with glaucoma.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 168 (estimated)
- First submitted
- 21 Sept 2023
- Start date
- 1 Dec 2023
- Primary completion date
- 31 Mar 2026
- Lead sponsor
- Henner Hanssen
- Diseases
- Glaucoma
- NCT number
- NCT06058598
What you commit to
- Study type: Interventional
- Planned participants: 168
- From 1 Dec 2023 to the primary completion date, 31 Mar 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Patients having had glaucoma surgery within 6 months before start of the project
- Patients with changes in topical medication or laser trabeculoplasty within 3 months before start of the project
Other illness
- Patients with life-threatening arrhythmia, signs of ischemia during CPET which preclude participation in an exercise trial
- Patients with insulin treated diabetes, chronic obstructive pulmonary disease or cancer.
Other
- Patients with very severe glaucoma (visual field mean deviation lower than -12Db)
- Significant opacification of ocular media
- Patients doing ≥1 structured exercise training session per week or \>150min of exercise/week assessed via the following two questions: a. On average, how many days per week do you engage in moderate to vigorous physical activity (like brisk walking)? b. On average, how many minutes per day do you engage in physical activity at this level? Calculate the total weekly minutes of exercise by multiplying a times b.
- Mental or physical limitation precluding participation in a high intensity exercise program
Who the study is looking for
- Voluntary written informed consent of the participant has been obtained prior to any screening procedures
- Patients with primary open angle glaucoma (POAG), high tension glaucoma (HTG) and normal tension glaucoma (NTG), aged 40 - 75 years
- In regular follow-up in either of the two study centres
Age in the registry: 40 years to 80 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Basel, Department of Sport, Exercise & Health Coordinator of this site? Confirm its status | Basel | Switzerland | Unknown status |
Related publications
- Cardiorespiratory Fitness, Cardiovascular Risk, and Disease-Related Outcomes in Primary Open-Angle Glaucoma: A Cross-Sectional Study.Ophthalmol Glaucoma · 2026 · PMID 42772519
This page is information, not medical advice. Discuss any trial with your doctor.