NCT06059027Completed
Microbes and Respiratory Illnesses
Microbes and Respiratory Illnesses, The MARI Study
Source: ClinicalTrials.gov · Last updated 16 Jan 2026
Brief summary (registry, in English)
This study is called the Microbes and Respiratory Illnesses (MARI) Study. Children growing up on farms are exposed to many types of microbes that could be beneficial. It is thought that increased exposure to certain types of microbes early in life helps to develop a healthy immune system and reduce the risk for severe common cold illnesses, breathing problems, and allergies.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 290 (actual)
- First submitted
- 22 Sept 2023
- Start date
- 18 Oct 2023
- Primary completion date
- 6 Nov 2025
- Lead sponsor
- University of Wisconsin, Madison
- Diseases
- Asthma
- NCT number
- NCT06059027
What you commit to
- Study type: Observational
- Participants enrolled: 290
- From 18 Oct 2023 to the primary completion date, 6 Nov 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Chronic sinusitis (frequent sinus infections)
Lab values
- Past or current medical problems or findings from physical examination or laboratory testing that are not listed above, which, in the opinion of the investigator, may pose additional risks from participation in the study, may interfere with the participant's ability to comply with study requirements or that may impact the quality or interpretation of the data obtained from the study
Other
- Inability or unwillingness of a participant to give written informed consent or comply with study protocol
- Plans to move out of the area before completing the study
- Enrolled family member
Who the study is looking for
- Participant and/or parent guardian must be able to understand and provide informed consent
- Children ages 4-12 years of age
- Cohort 1: Family is self-identified as Traditional agrarian (TA) Community member
- Cohort 2: Madison-area children with parental report of doctor-diagnosed asthma
- Cohort 3: Madison-area children with no history of asthma by parental report
- Cohort 4: Madison-area children who have an active respiratory illness
Age in the registry: 4 years to 12 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Wisconsin School of Medicine and Public Health Coordinator of this site? Confirm its status | Madison | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.