NCT06059651Completed
The Effects of Metabolic & Bariatric Surgery on Lipid Metabolism, Myeloid-Derived Suppressor Cells, and Cancer Cell Biology
Source: ClinicalTrials.gov · Last updated 15 Sept 2026
Brief summary (registry, in English)
This study aims to determine the relationship between lipid metabolic alterations associated with insulin resistance changes, and blood immunosuppressive-type cells (MDSC) by metabolic and bariatric surgery in two patient cohorts matched on demographic and clinical factors
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 11 (actual)
- First submitted
- 22 Sept 2023
- Start date
- 1 Jan 2024
- Primary completion date
- 1 Mar 2026
- Lead sponsor
- Pennington Biomedical Research Center
- Diseases
- Obesity
- NCT number
- NCT06059651
What you commit to
- Study type: Observational
- Participants enrolled: 11
- From 1 Jan 2024 to the primary completion date, 1 Mar 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Criteria the registry did not label
- For an eligible subject, all the following must be answered "yes":
- Biological female sex
- Age \>=35 and \<=60 years (including pre- and postmenopausal)
- Self-reported white or black race
- The study will enroll approximately 50% white and 50% black subjects
- Body mass index \>/=40 kg/m2
- Planned to have bariatric surgery or post-bariatric surgery
- Ability to provide written informed consent
- Allow the collection and storage of biospecimens and data for future use
- Not having yet started the pre-op liquid diet before the bariatric surgery
- For an eligible subject, all the following must be answered "no":
- Have type one diabetes
- Use of anti-inflammatory medications, such as glucocorticoids or non-steroidal anti-inflammatory medications, within the past 15 days
- History of cancer of any type
- History of chronic conditions known to cause inflammation, such as tuberculosis, autoimmune disease, and human immunodeficiency virus
- An acute history (within the past 60 days) or confirmed or suspected SARS-CoV-2 (COVID-19) infection
- Currently pregnant, breastfeeding, or planning to become pregnant within the next 52 weeks
- Currently participating in another study with competing outcomes
- Any other situation that, in the opinion of the investigator, would negatively impact subject safety or successful compliance with the protocol
Age in the registry: 35 years to 60 years · Sex: Female · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Pennington Biomedical Resarch Center Coordinator of this site? Confirm its status | Baton Rouge | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.