NCT06061042Recruiting
Effect of Timed-Restricted Eating on Metabolic Health
The Effect of Timed-Restricted Eating on Insulin Sensitivity, De Novo Lipogenesis and Liver Fat in Subjects With Obesity and Insulin Resistance
Source: ClinicalTrials.gov · Last updated 29 Sept 2023 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
We aim to determine the effect of combined isocaloric time restricted eating and meal timing on metabolic health, liver fat, functional brain networks, inflammation, and sleep pattern/quality in subjects with obesity and insulin resistance.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 30 (estimated)
- First submitted
- 24 Sept 2023
- Start date
- Oct 2023
- Primary completion date
- Dec 2027
- Lead sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
- Diseases
- Obesity, Fatty liver disease (MASLD/MASH)
- NCT number
- NCT06061042
What you commit to
- Study type: Interventional
- Planned participants: 30
- From Oct 2023 to the primary completion date, Dec 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Drugs abuse or alcohol abuse (\>3 units/day);
Other illness
- Use of any medication, except for those related to treatment of metabolic syndrome;
- Any medical condition interfering with study outcomes or design;
- History of any psychiatric disorder, including eating disorders;
- Known soy, egg, milk or peanut allergy;
Other
- Performing shift work
- Performing intensive sports (\>3 hours/week);
- Smoking;
- Contraindication for MRI;
- Known lactose/gluten intolerance;
- Childhood onset of obesity
Who the study is looking for
- Ability to provide informed consent;
- BMI \> 30kg/m\^2;
- Insulin resistance, as defined by fasting plasma insulin \> 62 pmol/L and/or prediabetes, as defined by fasting plasma glucose \> 5.3 and \< 7.0 mmol/L;
- Stable weight for 3 months prior to study inclusion
- For women, 1 year after last menstrual cycle
Age in the registry: 50 years to 75 years · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Amsterdam UMC, location AMC Coordinator of this site? Confirm its status | Amsterdam | Netherlands | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.