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NCT06063603Completed

Evaluation of a Pain Management Intervention Preparatory to a Future Pragmatic Trial, ASCENT Study

Pilot Test of a Pain Management Intervention Preparatory to a Future Pragmatic Trial (ASCENT)

Source: ClinicalTrials.gov · Last updated 18 Sept 2025

Brief summary (registry, in English)

This clinical trial tests how well a pain management intervention preparatory to a future pragmatic trial works in rural dwelling and Hispanic cancer survivors. Cancer pain is a key case study in health disparities in the United States. Cancer pain is prevalent, under treated, and remains a major cause of suffering, impairment, and disability for millions of Americans. Individual pain interventions and care models show promise for cancer pain in controlled settings. Hispanic and rural-dwelling cancer survivors stand to benefit the most from electronic health record innovations, as each of these health disparities populations experience profound disparities in pain outcomes, including marked under- and over-prescribing of opioids. Additionally, Hispanics not only comprise a steadily growing proportion of cancer survivors, but are also increasingly immigrating to rural communities, potentially placing them at "double risk" for poor outcomes. This trial will allow for the refinement of pain management intervention components that could help the management of cancer-related pain in rural dwelling and Hispanic cancer survivors.

Status (registry)
Completed
Study type
Interventional
Enrollment
51 (actual)
First submitted
13 Sept 2023
Start date
22 May 2023
Primary completion date
2 Feb 2024
Lead sponsor
Mayo Clinic
NCT number
NCT06063603

What you commit to

  • Study type: Interventional
  • Participants enrolled: 51
  • From 22 May 2023 to the primary completion date, 2 Feb 2024
  • 2 sites in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other

  • Patient Health Questionnaire (PHQ) 8 score of 10 or more
  • Life expectancy less than 12 months
  • Hospice enrollment
  • Admitted to hospital from long term care/skilled nursing facilities (SNF)
  • Acute leukemias
  • Primary brain tumors
  • Confinement to a bed or a chair more than a third of waking hours because of health complications

Who the study is looking for

  • A qualifying liquid or solid cancer diagnosis with visits at a participating Mayo site
  • Age 18+
  • Numerical rating scale (NRS) pain score of a 5+ out of 10
  • Pain that developed (onset) or significantly worsened since cancer diagnosis
  • Malignant hematology including:
    • Lymphoma
    • Myeloma
    • Chronic leukemias

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (2)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Mayo Clinic in Rochester
Coordinator of this site? Confirm its status
RochesterUnited StatesUnknown status
Mayo Clinic in Arizona
Coordinator of this site? Confirm its status
ScottsdaleUnited StatesUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.