NCT06064682Recruiting
An Organoid-based Functional Precision Medicine Trial in Osteosarcoma
An Organoid-based Functional Precision Medicine Trial in Osteosarcoma: PREMOST
Source: ClinicalTrials.gov · Last updated 11 May 2026
Brief summary (registry, in English)
The purpose of this study is to examine if we can predict sensitivity of osteosarcoma to different chemotherapy agents using tissue cultures in the laboratory. We know that different chemotherapy agents can be used in the treatment, but not every sarcoma responds to them equally. It is important to understand if testing of the tissue obtained during a routine biopsy or surgery may be useful in selecting appropriate treatments. In addition, additional testing of the tumor, including genetic testing, will help us to understand osteosarcoma better.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 40 (estimated)
- First submitted
- 26 Sept 2023
- Start date
- Feb 2024
- Primary completion date
- Jan 2027
- Lead sponsor
- Jonsson Comprehensive Cancer Center
- Diseases
- Childhood cancers, Sarcoma
- NCT number
- NCT06064682
What you commit to
- Study type: Observational
- Planned participants: 40
- From Feb 2024 to the primary completion date, Jan 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Criteria the registry did not label
- Inclusion / exclusion criteria - Group1:
- \- Patients without diagnosis of osteosarcoma and whose imaging studies are suggestive of osteosarcoma and who are planned to undergo biopsy or surgery for diagnostic purposes
- Inclusion / exclusion criteria - Group 2:
- \- Patients whose imaging studies are suggestive of metastatic osteosarcoma and who are planned to undergo biopsy or surgery for diagnostic purposes
Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| UCLA / Jonsson Comprehensive Cancer Center Coordinator of this site? Confirm its status | Los Angeles | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.