NCT06068647Recruiting
Ultrasound and Respiratory Physiological Signals in Lung Diseases
Synergistic Assessment of Ultrasound Data and Respiratory physiOlogical Signals in luNg Diseases
Source: ClinicalTrials.gov · Last updated 20 May 2026
Brief summary (registry, in English)
The use of lung ultrasound is instrumental in the evaluation of many chest pathologies and its ability to detect pleuro-pulmonary pathology is widely accepted. However, the use of ultrasound to explore the state of the peripheral lung parenchyma, when the organ is still aerated, is a relatively new application. Horizontal and vertical artifacts are separate and distinct artifacts that can be seen during ultrasound examination of the lungs. While the practical role of lung ultrasound artifacts is accepted to detect and monitor many conditions, further research is needed for the physical interpretation of ultrasound artifacts. These artifacts are diagnostic signs, but we don't fully understand their origin. The artifactual information deriving from the surface acoustic interaction, beyond the pleural line, in the ultrasound images of the normally aerated and non-deflated lung, represents the final result of complex interactions of acoustic waves with a specific three-dimensional structure of the biological tissue. Thus, the umbrella term "vertical artifacts" oversimplifies many physical phenomena associated with a pathological pleural plane. There is growing evidence that vertical artifacts are caused by physiological and pathological changes in the superficial lung parenchyma. Therefore, the need emerges to explore the physical phenomena underlying the artifactual ultrasound information deriving from the surface acoustic interaction of ultrasound with the pleuro-pulmonary structures.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 25 (estimated)
- First submitted
- 5 Jun 2023
- Start date
- 22 Mar 2023
- Primary completion date
- 30 Jun 2026
- Lead sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
- Diseases
- COPD
- NCT number
- NCT06068647
What you commit to
- Study type: Interventional
- Planned participants: 25
- From 22 Mar 2023 to the primary completion date, 30 Jun 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Presence of electromagnetic disturbances or significant ionizing radiation sources which might lead to signal artifacts.
Other illness
- history of skin irritation, redness, itching or allergic cutaneous symptoms.
- Allergic reactions to adhesives or hydrogels.
- Family history of adhesive skin allergies.
- Presence of severe skin conditions such as wounds, burns or on any damaged skin.
- Use of external cardiac defibrillators.
- Use of extra cardiac stimulators.
Other
- Presence of strong magnetic fields in the study setting.
- Use of diaphragmatic pacers.
- Pregnancy.
- Pediatric population.
Who the study is looking for
- inpatients admitted to the hospital due to diffuse interstitial lung diseases during exacerbation OR infectious interstitial pneumonia not caused by SARS-CoV-2 OR acute exacerbation of chronic obstructive pulmonary disease.
- Outpatients with pulmonary paraseptal and/or panlobular emphysema and/or chronic obstructive pulmonary disease during stable phase.
- Patients able to give written informed consent.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Fondazione Policlinico Universitario A. Gemelli IRCCS Coordinator of this site? Confirm its status | Rome | Italy | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.