NCT06068842Completed
A Study to Assess Prevalence of a Specific Protein Overexpression in Adult Participants With Non-Small Cell Lung Cancer
International Real-World Study of MET Overexpression in Patients With Non-Small Cell Lung Cancer
Source: ClinicalTrials.gov · Last updated 29 Jan 2025
Brief summary (registry, in English)
Non-small cell lung cancer (NSCLC) is the most common type of lung cancer, accounting for 80%-85% of lung cancers cases of which 60% are non-squamous (NSQ). This study will evaluate the prevalence of mesenchymal epithelial transition (MET) overexpression (OE) in adult participants with advanced or metastatic NSQ NSCLC. Archived tissue biopsies will be tested for MET OE and data from approximately 500 participants will be collected. No participants will be enrolled in this study. Participants' charts will be reviewed. No drug will be administered as a part of this study. The duration of the study will be approximately 15 months. There is no additional burden for participants in this trial.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 579 (actual)
- First submitted
- 29 Sept 2023
- Start date
- 3 Nov 2023
- Primary completion date
- 31 Dec 2024
- Lead sponsor
- AbbVie
- Diseases
- Lung cancer
- NCT number
- NCT06068842
What you commit to
- Study type: Observational
- Participants enrolled: 579
- From 3 Nov 2023 to the primary completion date, 31 Dec 2024
- 19 sites in 12 countries
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Specimens collected before 2019.
- Insufficient specimen tissue for testing.
- Insufficient specimen quality (e.g., not 4-5 µm in thickness) which precludes testing.
- Adenosquamous and sarcomatous histologies of NSCLC.
Who the study is looking for
- Previously consented and/or prospective collection of consent for research use of banked biological materials and clinical data.
- Confirmed advanced and/or metastatic non-squamous (NSQ) non-small cell lung cancer (NSCLC).
- Has formalin-fixed paraffin-embedded (FFPE) tissue collected since 2019.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (19)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Burjeel Medical City /ID# 259407 Coordinator of this site? Confirm its status | Abu Dhabi | United Arab Emirates | Unknown status |
| Hospital Italiano de Buenos Aires /ID# 256999 Coordinator of this site? Confirm its status | Ciudad Autonoma Buenos Aires | Argentina | Unknown status |
| Instituto Alexander Fleming /ID# 256295 Coordinator of this site? Confirm its status | Ciudad Autonoma de Buenos Aire | Argentina | Unknown status |
| Irmandade da Santa Casa de Misericordia de Porto Alegre /ID# 256487 Coordinator of this site? Confirm its status | Porto Alegre | Brazil | Unknown status |
| Hospital Alemao Oswaldo Cruz /ID# 256486 Coordinator of this site? Confirm its status | São Paulo | Brazil | Unknown status |
| Nova Scotia Health Authority /ID# 256950 Coordinator of this site? Confirm its status | Halifax | Canada | Unknown status |
| Institut universitaire de cardiologie et de pneumologie de Québec - Université L /ID# 257872 Coordinator of this site? Confirm its status | Québec | Canada | Unknown status |
| Royal University Hospital /ID# 261272 Coordinator of this site? Confirm its status | Saskatoon | Canada | Unknown status |
| Universitätsspital Basel /ID# 256677 Coordinator of this site? Confirm its status | Basel Town | Switzerland | Unknown status |
| University Hospital Zurich /ID# 256678 Coordinator of this site? Confirm its status | Zurich | Switzerland | Unknown status |
| West China Hospital, Sichuan University /ID# 256906 Coordinator of this site? Confirm its status | Chengdu | China | Unknown status |
| UOMi Cancer Center - Clinica Tres Torres /ID# 261212 Coordinator of this site? Confirm its status | Barcelona | Spain | Unknown status |
| Queen's University Belfast /ID# 258458 Coordinator of this site? Confirm its status | Belfast | United Kingdom | Unknown status |
| University Hospitals Birmingham NHS Foundation Trust /ID# 260991 Coordinator of this site? Confirm its status | Birmingham | United Kingdom | Unknown status |
| Rambam Health Care Campus /ID# 256546 Coordinator of this site? Confirm its status | Haifa | Israel | Unknown status |
| National Cancer Center Hospital /ID# 257889 Coordinator of this site? Confirm its status | Chuo-ku | Japan | Unknown status |
| Kindai University Hospital /ID# 257890 Coordinator of this site? Confirm its status | Osakasayama-shi | Japan | Unknown status |
| The Catholic University of Korea, Yeouido ST. Mary's Hospital /ID# 261511 Coordinator of this site? Confirm its status | Seoul | South Korea | Unknown status |
| National Taiwan University Hospital /ID# 261542 Coordinator of this site? Confirm its status | Taipei City | Taiwan | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.