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NCT06068842Completed

A Study to Assess Prevalence of a Specific Protein Overexpression in Adult Participants With Non-Small Cell Lung Cancer

International Real-World Study of MET Overexpression in Patients With Non-Small Cell Lung Cancer

Source: ClinicalTrials.gov · Last updated 29 Jan 2025

Brief summary (registry, in English)

Non-small cell lung cancer (NSCLC) is the most common type of lung cancer, accounting for 80%-85% of lung cancers cases of which 60% are non-squamous (NSQ). This study will evaluate the prevalence of mesenchymal epithelial transition (MET) overexpression (OE) in adult participants with advanced or metastatic NSQ NSCLC. Archived tissue biopsies will be tested for MET OE and data from approximately 500 participants will be collected. No participants will be enrolled in this study. Participants' charts will be reviewed. No drug will be administered as a part of this study. The duration of the study will be approximately 15 months. There is no additional burden for participants in this trial.

Status (registry)
Completed
Study type
Observational
Enrollment
579 (actual)
First submitted
29 Sept 2023
Start date
3 Nov 2023
Primary completion date
31 Dec 2024
Lead sponsor
AbbVie
Diseases
Lung cancer
NCT number
NCT06068842

What you commit to

  • Study type: Observational
  • Participants enrolled: 579
  • From 3 Nov 2023 to the primary completion date, 31 Dec 2024
  • 19 sites in 12 countries
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other

  • Specimens collected before 2019.
  • Insufficient specimen tissue for testing.
  • Insufficient specimen quality (e.g., not 4-5 µm in thickness) which precludes testing.
  • Adenosquamous and sarcomatous histologies of NSCLC.

Who the study is looking for

  • Previously consented and/or prospective collection of consent for research use of banked biological materials and clinical data.
  • Confirmed advanced and/or metastatic non-squamous (NSQ) non-small cell lung cancer (NSCLC).
  • Has formalin-fixed paraffin-embedded (FFPE) tissue collected since 2019.

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (19)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Burjeel Medical City /ID# 259407
Coordinator of this site? Confirm its status
Abu DhabiUnited Arab EmiratesUnknown status
Hospital Italiano de Buenos Aires /ID# 256999
Coordinator of this site? Confirm its status
Ciudad Autonoma Buenos AiresArgentinaUnknown status
Instituto Alexander Fleming /ID# 256295
Coordinator of this site? Confirm its status
Ciudad Autonoma de Buenos AireArgentinaUnknown status
Irmandade da Santa Casa de Misericordia de Porto Alegre /ID# 256487
Coordinator of this site? Confirm its status
Porto AlegreBrazilUnknown status
Hospital Alemao Oswaldo Cruz /ID# 256486
Coordinator of this site? Confirm its status
São PauloBrazilUnknown status
Nova Scotia Health Authority /ID# 256950
Coordinator of this site? Confirm its status
HalifaxCanadaUnknown status
Institut universitaire de cardiologie et de pneumologie de Québec - Université L /ID# 257872
Coordinator of this site? Confirm its status
QuébecCanadaUnknown status
Royal University Hospital /ID# 261272
Coordinator of this site? Confirm its status
SaskatoonCanadaUnknown status
Universitätsspital Basel /ID# 256677
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Basel TownSwitzerlandUnknown status
University Hospital Zurich /ID# 256678
Coordinator of this site? Confirm its status
ZurichSwitzerlandUnknown status
West China Hospital, Sichuan University /ID# 256906
Coordinator of this site? Confirm its status
ChengduChinaUnknown status
UOMi Cancer Center - Clinica Tres Torres /ID# 261212
Coordinator of this site? Confirm its status
BarcelonaSpainUnknown status
Queen's University Belfast /ID# 258458
Coordinator of this site? Confirm its status
BelfastUnited KingdomUnknown status
University Hospitals Birmingham NHS Foundation Trust /ID# 260991
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BirminghamUnited KingdomUnknown status
Rambam Health Care Campus /ID# 256546
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HaifaIsraelUnknown status
National Cancer Center Hospital /ID# 257889
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Chuo-kuJapanUnknown status
Kindai University Hospital /ID# 257890
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Osakasayama-shiJapanUnknown status
The Catholic University of Korea, Yeouido ST. Mary's Hospital /ID# 261511
Coordinator of this site? Confirm its status
SeoulSouth KoreaUnknown status
National Taiwan University Hospital /ID# 261542
Coordinator of this site? Confirm its status
Taipei CityTaiwanUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.