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NCT06070961Active, not recruiting

Prospective Biological Study to Evaluate the Persistence of COVID-19 Vaccine and Other Vaccines'-Induced Immune Responses in Follicular Lymphoma Patients Undergoing Frontline Induction Immuno-chemotherapy and Anti-CD20 Maintenance

Source: ClinicalTrials.gov · Last updated 26 Jun 2026

Brief summary (registry, in English)

This is a prospective biological study evaluating the persistence of COVID-19 vaccine and other vaccines' (zoster, diphtheria and tetanus)-induced immunity in a subgroup patient affected by Follicular Lymphoma requiring treatment undergoing frontline induction immuno-chemotherapy and anti-CD20 maintenance within the prospective FIL\_FOLL19 study (NCT05058404). Blood samples from patients will be collected before and at planned timepoints during treatment to evaluate humoral and cellular immunity against SARS-COV-2, VZV, tetanus and diphtheria and T-cell markers characterization.

Status (registry)
Active, not recruiting
Study type
Observational
Enrollment
56 (actual)
First submitted
3 Oct 2023
Start date
7 May 2024
Primary completion date
May 2027
Lead sponsor
Fondazione Italiana Linfomi - ETS
NCT number
NCT06070961

What you commit to

  • Study type: Observational
  • Participants enrolled: 56
  • From 7 May 2024 to the primary completion date, May 2027
  • 14 sites in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study design.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other

  • None

Who the study is looking for

  • Enrolment in FIL\_FOLL19 study
  • Previous vaccination for COVID-19 (at least 3 doses)
  • Availability of informations about COVID-19 and other vaccines previously administered (vaccination records)
  • Willingness to comply with blood collection timepoints required for vaccination immunity evaluation
  • Signature of specific informed consent form

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (14)

Sites in registry order. Save your city in your profile to sort them by distance.

SiteCityCountrySite status
A.O. SS. Antonio e Biagio e Cesare Arrigo, S.C. Ematologia
Coordinator of this site? Confirm its status
AlessandriaItalyUnknown status
Azienda Ospedaliera S.Giuseppe Moscati - S.C. Ematologia e Trapianto emopoietico
Coordinator of this site? Confirm its status
AvellinoItalyUnknown status
Nuovo Ospedale degli Infermi, SSD Ematologia
Coordinator of this site? Confirm its status
BiellaItalyUnknown status
Azienda Ospedaliera Universitaria Careggi - Unità funzionale di Ematologia
Coordinator of this site? Confirm its status
FlorenceItalyUnknown status
Ospedale Maggiore Policlinico Fondazione IRCCS Ca' Granda - Ematologia
Coordinator of this site? Confirm its status
MilanItalyUnknown status
ASST Grande Ospedale Metropolitano Niguarda - SC Ematologia
Coordinator of this site? Confirm its status
MilanItalyUnknown status
A.O.U. Maggiore della Carità di Novara - S.C.D.U. Ematologia
Coordinator of this site? Confirm its status
NovaraItalyUnknown status
IRCCS Policlinico San Matteo - Divisione di Ematologia
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PaviaItalyUnknown status
Ospedale Guglielmo da Saliceto - U.O. Ematologia
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PiacenzaItalyUnknown status
Ospedale delle Croci, Ematologia
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RavennaItalyUnknown status
Azienda Unità Sanitaria Locale-IRCCS - Arcispedale Santa Maria Nuova - Ematologia
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Reggio EmiliaItalyUnknown status
A.O.U. Senese - U.O.C. Ematologia
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SienaItalyUnknown status
A.O.U. Città della Salute e della Scienza di Torino - S.C. Ematologia
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TorinoItalyUnknown status
A.O.U. Città della Salute e della Scienza di Torino - S.C. Ematologia U
Coordinator of this site? Confirm its status
TorinoItalyUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.