NCT06070961Active, not recruiting
Prospective Biological Study to Evaluate the Persistence of COVID-19 Vaccine and Other Vaccines'-Induced Immune Responses in Follicular Lymphoma Patients Undergoing Frontline Induction Immuno-chemotherapy and Anti-CD20 Maintenance
Source: ClinicalTrials.gov · Last updated 26 Jun 2026
Brief summary (registry, in English)
This is a prospective biological study evaluating the persistence of COVID-19 vaccine and other vaccines' (zoster, diphtheria and tetanus)-induced immunity in a subgroup patient affected by Follicular Lymphoma requiring treatment undergoing frontline induction immuno-chemotherapy and anti-CD20 maintenance within the prospective FIL\_FOLL19 study (NCT05058404). Blood samples from patients will be collected before and at planned timepoints during treatment to evaluate humoral and cellular immunity against SARS-COV-2, VZV, tetanus and diphtheria and T-cell markers characterization.
- Status (registry)
- Active, not recruiting
- Study type
- Observational
- Enrollment
- 56 (actual)
- First submitted
- 3 Oct 2023
- Start date
- 7 May 2024
- Primary completion date
- May 2027
- Lead sponsor
- Fondazione Italiana Linfomi - ETS
- Diseases
- Follicular lymphoma
- NCT number
- NCT06070961
What you commit to
- Study type: Observational
- Participants enrolled: 56
- From 7 May 2024 to the primary completion date, May 2027
- 14 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study design.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- None
Who the study is looking for
- Enrolment in FIL\_FOLL19 study
- Previous vaccination for COVID-19 (at least 3 doses)
- Availability of informations about COVID-19 and other vaccines previously administered (vaccination records)
- Willingness to comply with blood collection timepoints required for vaccination immunity evaluation
- Signature of specific informed consent form
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (14)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| A.O. SS. Antonio e Biagio e Cesare Arrigo, S.C. Ematologia Coordinator of this site? Confirm its status | Alessandria | Italy | Unknown status |
| Azienda Ospedaliera S.Giuseppe Moscati - S.C. Ematologia e Trapianto emopoietico Coordinator of this site? Confirm its status | Avellino | Italy | Unknown status |
| Nuovo Ospedale degli Infermi, SSD Ematologia Coordinator of this site? Confirm its status | Biella | Italy | Unknown status |
| Azienda Ospedaliera Universitaria Careggi - Unità funzionale di Ematologia Coordinator of this site? Confirm its status | Florence | Italy | Unknown status |
| Ospedale Maggiore Policlinico Fondazione IRCCS Ca' Granda - Ematologia Coordinator of this site? Confirm its status | Milan | Italy | Unknown status |
| ASST Grande Ospedale Metropolitano Niguarda - SC Ematologia Coordinator of this site? Confirm its status | Milan | Italy | Unknown status |
| A.O.U. Maggiore della Carità di Novara - S.C.D.U. Ematologia Coordinator of this site? Confirm its status | Novara | Italy | Unknown status |
| IRCCS Policlinico San Matteo - Divisione di Ematologia Coordinator of this site? Confirm its status | Pavia | Italy | Unknown status |
| Ospedale Guglielmo da Saliceto - U.O. Ematologia Coordinator of this site? Confirm its status | Piacenza | Italy | Unknown status |
| Ospedale delle Croci, Ematologia Coordinator of this site? Confirm its status | Ravenna | Italy | Unknown status |
| Azienda Unità Sanitaria Locale-IRCCS - Arcispedale Santa Maria Nuova - Ematologia Coordinator of this site? Confirm its status | Reggio Emilia | Italy | Unknown status |
| A.O.U. Senese - U.O.C. Ematologia Coordinator of this site? Confirm its status | Siena | Italy | Unknown status |
| A.O.U. Città della Salute e della Scienza di Torino - S.C. Ematologia Coordinator of this site? Confirm its status | Torino | Italy | Unknown status |
| A.O.U. Città della Salute e della Scienza di Torino - S.C. Ematologia U Coordinator of this site? Confirm its status | Torino | Italy | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.