NCT06073106Recruiting
Targeting Osteosarcopaenia and Multimorbidity for Frailty Prevention
Targeting Osteosarcopaenia and Multimorbidity for Frailty Prevention Through Identification and Deep Phenotyping Methods in Healthy Aging and High-burden Disease Cohorts.
Source: ClinicalTrials.gov · Last updated 2 Oct 2026
Brief summary (registry, in English)
The aging population and its accompanying burden from non-communicable chronic diseases predicts an increasing impact imposed by frailty on healthcare systems. This is due to a lack of normative data for older adults and reliable risk stratification methods to develop effective approaches to the prevention of frailty. In this study, the investigators plan to form a common dataset for phenotype identification, risk stratification of frailty and its targeted treatment plans in the at-risk and mildly frail population.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 500 (estimated)
- First submitted
- 20 Sept 2023
- Start date
- 1 Jan 2025
- Primary completion date
- Jan 2027
- Lead sponsor
- Tan Tock Seng Hospital
- Diseases
- Stroke
- NCT number
- NCT06073106
What you commit to
- Study type: Observational
- Planned participants: 500
- From 1 Jan 2025 to the primary completion date, Jan 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Previous knee arthroplasty
Other illness
- Impairments affecting understanding of questionnaires and tasks: e.g. severe deafness, severe visual impairment and severe /global aphasia,
- Presence of active fractures, dislocations, non-weight bearing status, burns, unhealed wounds, active skin infections/eczema and agitated behaviour or delirium
- Presence of tracheostomy, ventilator, renal dialysis, end-organ failure
- Patients with disorders of consciousness.
Other
- Nursing home or dormitory resident
- Non-resident status in Singapore (e.g. foreign worker, tourist, temporary visit pass)
- Anticipated life expectancy \< 1 year
- Pregnant or lactating participants
- For Knee Osteoarthritis patients only:
- Alternative diagnosis to knee OA e.g. Referred pain from hip or spine.
- Other forms of knee arthritis eg. Inflammatory, post traumatic
Who the study is looking for
- Age ≥ 50y
- Asian ethnicity
- First diagnosis (stroke, Traumatic Brain Injury (TBI), knee osteoarthritis, breast cancer)
- Living in community
- Able to understand 1 step simple commands
- For inpatients: (i) within 12 weeks of disease (stroke/TBI) onset, and (ii) within 2 weeks of rehabilitation ward admission
- For outpatients: (i) \>6 months from initial diagnosis of first stroke, TBI, knee osteoarthritis or breast cancer, and (ii) at least standby assistance, modified independent or independent in ambulation with /without walking.
Age in the registry: 50 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Tan Tock Seng Hospital Coordinator of this site? Confirm its status | Singapore | Singapore | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.