NCT06073704Recruiting
Effects of Adjunct Antimicrobial Photodynamic Therapy in Periodontal Treatment of Patients With Obesity
Effects of Antimicrobial Photodynamic Therapy in Non-surgical Periodontal Treatment of Patients With Obesity
Source: ClinicalTrials.gov · Last updated 4 May 2026
Brief summary (registry, in English)
The goal of this clinical trial is to compare the effects of adjuvant antimicrobial photodynamic therapy (aPDT) as an adjuvant of scaling and root planing with scaling and root planing alone for periodontal treatment in patients with periodontal disease and obesity. The main question it aims to answer are: Does adjuvant aPDT improves periodontal health? Are there differences in the proteomic profile of gingival fluid after both treatments? Participants will receive scaling and root planing complemented or not by aPDT. Results will be collected after 1, 3, and 6 months. Researchers will compare adjuvant aPDT treatment to regular treatment to see if it promotes reduction in inflammation and improvement in periodontal health.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 24 (estimated)
- First submitted
- 25 Sept 2023
- Start date
- 9 Oct 2023
- Primary completion date
- 30 Jul 2026
- Lead sponsor
- University of Sao Paulo
- Diseases
- Obesity
- NCT number
- NCT06073704
What you commit to
- Study type: Interventional
- Planned participants: 24
- From 9 Oct 2023 to the primary completion date, 30 Jul 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Alcohol or drugs consumption
- Use of drugs that alter periodontal structures as phenytoin or ciclosporin
Other illness
- Kidney disorders
Other
- Smokers
- Pregnancy or lactation
- Use of antibiotics at the last 30 days
- Periodontal treatment at the last 6 months
Who the study is looking for
- Obesity (grade II and III classified according to Body Mass Index)
- Periodontitis stage II to IV
- Presence of at least 20 teeth excluding 3rd molars.
Age in the registry: 18 years to 70 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Bauru School of Dentistry Coordinator of this site? Confirm its status | Bauru | Brazil | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.