NCT06080399Completed
Personality and Quality of Life Amelioration After Continuous Subcutaneous Apomorphine Infusion in Parkinson's Disease
Could Psycho-bio-social Context and Personality be a Predictive Factor of Quality of Life Amelioration After Continuous Subcutaneous Apomorphine Infusion in Parkinson's Disease Patients? - PERSO-PERF Study
Source: ClinicalTrials.gov · Last updated 12 May 2026
Brief summary (registry, in English)
Since our previous study has shown that some personality dimensions were associated with Quality of Life (QoL) amelioration after Deep Brain Stimulation (DBS) in Parkinson's disease (PD), the investigators aim to evaluate the impact of personality dimensions on therapeutic response after another second-line treatment: the continuous subcutaneous apomorphine infusion (CSAI). Moreover, the investigators would like to evaluate the potential evolution of personality dimensions through CSAI. The investigators also aim to evaluate other bio-psycho-social factors (representations of the disease, ways of copying and social support) influence on QoL amelioration after DBS.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 70 (actual)
- First submitted
- 6 Oct 2023
- Start date
- 15 Feb 2024
- Primary completion date
- 30 Mar 2026
- Lead sponsor
- University Hospital, Toulouse
- Diseases
- Parkinson disease
- NCT number
- NCT06080399
What you commit to
- Study type: Observational
- Participants enrolled: 70
- From 15 Feb 2024 to the primary completion date, 30 Mar 2026
- 10 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Patients presenting an atypical parkinsonian syndrome Patients having a Deep Brain Stimulation
- Patients with a psychiatric disease such as bipolar disorder or delusions linked to a dopaminergic psychosis
- Patient with a serious pathology (e.g. cancer) or a health condition which could interfere with the assessment of their quality of life, at the discretion of the investigator upon inclusion
Other
- Patients presenting a cognitive deficit attested by a score to the Montreal Cognitive Assessment inferior to 24, solely during the inclusion (baseline - V0)
- Patients under guardianship, curatorship or safeguard of justice
- Patients under exclusion period from another study
Who the study is looking for
- Parkinson's disease patients as defined by the United Kingdom Parkinson's disease Brain Bank (UKPDSBB) criteria and aged from 40 to 75 years old (included)
- Patients with motor fluctuations and/or invalidating dyskinesia and awaiting CSAI establishment in the context of their usual care for PD
- Patients affiliated to a social security system
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (10)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Chu de Lyon Coordinator of this site? Confirm its status | Bron | France | Unknown status |
| Hopital Gabriel Montpied Coordinator of this site? Confirm its status | Clermont-Ferrand | France | Unknown status |
| CHU de Grenoble Coordinator of this site? Confirm its status | Grenoble | France | Unknown status |
| CHU Limoges Coordinator of this site? Confirm its status | Limoges | France | Unknown status |
| CHU de Nancy Coordinator of this site? Confirm its status | Nancy | France | Unknown status |
| CHU de Nice Coordinator of this site? Confirm its status | Nice | France | Unknown status |
| CHU de Poitiers Coordinator of this site? Confirm its status | Poitiers | France | Unknown status |
| CHU de Rennes Coordinator of this site? Confirm its status | Rennes | France | Unknown status |
| CHU de Rouen Coordinator of this site? Confirm its status | Rouen | France | Unknown status |
| CHU de Toulouse Coordinator of this site? Confirm its status | Toulouse | France | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.