NCT06082518Active, not recruiting
Improving Post COVID-19 Syndrome With Hyperbaric Oxygen Treatments
Improving Post COVID-19 Syndrome With Hyperbaric Oxygen Treatments (PCS-HBOT Study)
Source: ClinicalTrials.gov · Last updated 2 Sept 2026
Brief summary (registry, in English)
Over 500 million people have been infected with COVID-19, and to date, more than 6 million people have died. Many individuals who have recovered from COVID-19 continue to experience symptoms even after they have been "cured" of the disease. This condition is known as post COVID-19 condition, which can have serious health consequences. A common symptom among these individuals is chronic fatigue, characterized by persistent tiredness or lack of energy. This study aims to explore a novel treatment for symptoms of post COVID-19 condition, known as hyperbaric oxygen therapy. This approach has shown promise in helping people with post COVID-19 conditions and treating some other causes of fatigue. Hyperbaric oxygen therapy involves placing patients in a small chamber where they receive high oxygen gas levels. However, this treatment is expensive and time-consuming, and it is unclear if this treatment can be effectively assessed in a large-scale research study. This small study will help us decide if conducting a large research study is feasible. The investigators aim to assess if hyperbaric oxygen therapy can improve symptoms of post COVID-19 condition, such as fatigue.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 40 (estimated)
- First submitted
- 11 Sept 2023
- Start date
- 2 Jan 2024
- Primary completion date
- Jul 2027
- Lead sponsor
- Sunnybrook Health Sciences Centre
- Diseases
- Long COVID and ME/CFS
- NCT number
- NCT06082518
What you commit to
- Study type: Interventional
- Planned participants: 40
- From 2 Jan 2024 to the primary completion date, Jul 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Contraindications/medically unfit to receive hyperbaric treatments at an outpatient facility (pneumothorax, in-patients, requiring infusions to maintain hemodynamics, active and unstable coronary disease)
- Patients with cognitive difficulties and/or mental retardation before COVID diagnosis
- History of traumatic brain injury
Age
- Known pregnancy or planning a pregnancy in women of childbearing age
Other
- Unlikely to comply with follow-up assessments (e.g. no fixed address, plans to move out of town)
Who the study is looking for
- Age ≥ 18 years old
- Officially diagnosed with post COVID-19 condition by a healthcare practitioner
- At least three months since SARS-CoV-2 infection
- Symptoms that persist more than 12 weeks:
- Chronic fatigue (must include) along with one of the following symptoms:
- Difficulty thinking or problem solving ('brain fog')
- Stress or anxiety
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Sunnybrook Health Sciences Centre Coordinator of this site? Confirm its status | Toronto | Canada | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.