NCT06086379Enrolling by invitation
Cognitive Rehabilitation Therapy for COVID-19
Cognitive Rehabilitation to Improve Functioning in Veterans Following COVID-19
Source: ClinicalTrials.gov · Last updated 15 Jul 2026
Brief summary (registry, in English)
Cognitive dysfunction, psychiatric symptoms, functional impairment, and disability following COVID-19 negatively impact Veterans' community functioning and quality of life, contribute to significant human suffering, and are costly to VHA. Rehabilitation is a critical priority for Veterans with long COVID. One promising treatment to improve functioning in Veterans with post-COVID-19 cognitive symptoms is Compensatory Cognitive Training (CCT). Previous studies have found that CCT is feasible, acceptable, and efficacious in Veteran populations with multiple sources of cognitive dysfunction. This randomized controlled trial aims to address important RR\&D priorities by examining feasibility, acceptability, and preliminary efficacy of a COVID-19-specific rehabilitation intervention, CCT for long COVID (CCT-C) compared to a robust control condition. The proposed study has the potential to improve cognitive function, functional independence, and quality of life for Veterans with late or delayed effects of secondary conditions related to COVID-19 infections.
- Status (registry)
- Enrolling by invitation
- Study type
- Interventional
- Enrollment
- 70 (estimated)
- First submitted
- 13 Oct 2023
- Start date
- 1 Jul 2024
- Primary completion date
- 30 Jun 2027
- Lead sponsor
- VA Office of Research and Development
- Diseases
- Long COVID and ME/CFS
- NCT number
- NCT06086379
What you commit to
- Study type: Interventional
- Planned participants: 70
- From 1 Jul 2024 to the primary completion date, 30 Jun 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Current substance abuse disorder, psychotic disorder, dementia, etc.
- History of moderate to severe brain injury with loss of consciousness \> 30 minutes
Other
- Auditory or visual impairments that would prevent the ability to participate in assessment procedures
- Invalid performance on one or more embedded performance validity tests (PVTs)
Who the study is looking for
- Veterans \> 18 years old who are able to provide informed consent
- Prior participation in SF Parent Study or LA Parent Study
- Report of cognitive symptoms that Veteran attributes to COVID-19 infection
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| VA San Diego Healthcare System, San Diego, CA Coordinator of this site? Confirm its status | San Diego | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.