NCT06087354Completed
Low vs. Air Oxygen Concentration CAPA-IVM Culture of Cumulus-oocyte Complexes
Effect of Low Versus Air Oxygen Concentration in In-vitro Maturation With Biphasic Capacitation-IVM (CAPA-IVM) Culture of Human Cumulus-oocyte Complexes in PCOS Patients: a Sibling Oocyte Pilot Study
Source: ClinicalTrials.gov · Last updated 3 Jun 2024
Brief summary (registry, in English)
IVM with a pre-maturation step, known as capacitation IVM (CAPA-IVM), has demonstrated enhanced maturation of human oocytes in vitro and successful live births. However, CAPA-IVM has shown lower rates of embryo formation when compared to conventional in vitro fertilization/ intra cytoplasmic sperm injection (IVF/ICSI) cycles. To optimize the CAPA-IVM culture system, this pilot study aims to evaluate the impact of low oxygen versus air oxygen concentrations on embryological outcomes in PCOS patients.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 20 (actual)
- First submitted
- 12 Oct 2023
- Start date
- 9 Nov 2023
- Primary completion date
- 30 Jan 2024
- Lead sponsor
- Mỹ Đức Hospital
- NCT number
- NCT06087354
What you commit to
- Study type: Interventional
- Participants enrolled: 20
- From 9 Nov 2023 to the primary completion date, 30 Jan 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Cases with severe male factor (concentration \<5 million/ml, cryptozoospermia, azoospermia)
- Oocyte donation
- Pre-implantation genetic testing
Who the study is looking for
- ≤38 years
- Having polycystic ovarian morphology: at least 25 follicles (2-9 mm) throughout the whole ovary and/or increased ovarian volume (\>10ml)
- Having at least 20 follicles on the Oocyte Pick-up day
- Patients consent to culture embryos to the blastocyst
Age in the registry: 18 years to 37 years · Sex: Female · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| My Duc Hospital Coordinator of this site? Confirm its status | Ho Chi Minh City | Vietnam | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.