NCT06087458Active, not recruitingPhase 1/2
Study of VOY-101 in Patients With Advanced Non-Neovascular Age-Related Macular Degeneration
Phase 1/2a Study of VOY-101 in Subjects With Advanced Non-Neovascular Age-Related Macular Degeneration (JOURNEY)
Source: ClinicalTrials.gov · Last updated 17 Aug 2026
Brief summary (registry, in English)
The Phase 1 safety study of VOY-101 is comprised of escalating dose Cohorts, followed by a Phase 2 at the recommended phase 2 dose.
- Status (registry)
- Active, not recruiting
- Phase (registry)
- Phase 1/2
- Study type
- Interventional
- Enrollment
- 60 (estimated)
- First submitted
- 12 Oct 2023
- Start date
- 21 Jun 2023
- Primary completion date
- Oct 2027
- Lead sponsor
- Perceive Biotherapeutics, Inc.
- Diseases
- Macular degeneration
- NCT number
- NCT06087458
What you commit to
- Study type: Interventional · Phase 1/2
- Planned participants: 60
- From 21 Jun 2023 to the primary completion date, Oct 2027
- 16 sites in 3 countries
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Are women of childbearing potential (WOCBP) and are pregnant or unwilling to use and document use of effective contraception for the duration of the study.
- Additional Systemic, Ocular, and Genetic Exclusion Criteria.
Who the study is looking for
- Are ≥60 years of age at the time of consent.
- Are willing and able to understand and provide written informed consent.
- Are willing and able to return for scheduled treatment and follow-up examinations.
- Are able to undergo ETDRS BCDVA testing and ophthalmic imaging.
- Well-demarcated GA secondary to AMD in the absence of MNV and in the absence of history of MNV for both eyes.
- Absence of signs of non-exudative MNV.
- Additional Ocular Inclusion Criteria for both eyes.
- Meet certain genotype criteria for risk of AMD.
Age in the registry: 60 years to - · Sex: All · Does not accept healthy volunteers
Sites (16)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Cerulea Clinical Trials Coordinator of this site? Confirm its status | East Melbourne | Australia | Unknown status |
| Sydney Retina Clinic and Day Surgery Coordinator of this site? Confirm its status | Sydney | Australia | Unknown status |
| Rambam Medical Center Coordinator of this site? Confirm its status | Haifa | Israel | Unknown status |
| Tel-Aviv Sourasky Medical Center, Ophthalmology Division Coordinator of this site? Confirm its status | Tel Aviv | Israel | Unknown status |
| Austin Research Center for Retina Coordinator of this site? Confirm its status | Austin | United States | Unknown status |
| Ophthalmic Consultants of Boston Coordinator of this site? Confirm its status | Boston | United States | Unknown status |
| Mid Atlantic Retina Coordinator of this site? Confirm its status | Cherry Hill | United States | Unknown status |
| Star Retina Coordinator of this site? Confirm its status | Fort Worth | United States | Unknown status |
| Retina Northwest Coordinator of this site? Confirm its status | Portland | United States | Unknown status |
| Retina Consultants San Diego Coordinator of this site? Confirm its status | Poway | United States | Unknown status |
| Black Hills Regional Eye Institute Coordinator of this site? Confirm its status | Rapid City | United States | Unknown status |
| Retinal Consultants Medical Group Coordinator of this site? Confirm its status | Sacramento | United States | Unknown status |
| University of Utah John A. Moran Eye Center Coordinator of this site? Confirm its status | Salt Lake City | United States | Unknown status |
| Retina Macula Institute of AZ Coordinator of this site? Confirm its status | Scottsdale | United States | Unknown status |
| Retina Center of Texas Coordinator of this site? Confirm its status | Southlake | United States | Unknown status |
| The Retina Institute Coordinator of this site? Confirm its status | St Louis | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.