NCT06095271Active, not recruiting
MultiSCRIPT-Cycle 1: Personalized Medicine in Multiple Sclerosis - Pragmatic Platform Trial Embedded Within the SMSC
A Multicenter, Randomized Pragmatic Platform Trial Embedded Within the Swiss Multiple Sclerosis Cohort (SMSC) on Neurofilament Light Chain Monitoring Added to Usual Care to Inform Personalized Treatment Decisions in Multiple Sclerosis
Source: ClinicalTrials.gov · Last updated 11 May 2025
Brief summary (registry, in English)
This is a randomized pragmatic clinical trial fully embedded in the Swiss Multiple Sclerosis Cohort to assess whether sNfL biomarker monitoring improves patient-relevant outcomes and care of patients with relapsing-remitting (RR)MS by either increasing the proportion of patients with no evidence of disease activity (EDA) or by improving patients' health-related quality of life.
- Status (registry)
- Active, not recruiting
- Study type
- Interventional
- Enrollment
- 920 (actual)
- First submitted
- 10 Oct 2023
- Start date
- 5 Feb 2023
- Primary completion date
- Nov 2026
- Lead sponsor
- University Hospital, Basel, Switzerland
- Diseases
- Multiple sclerosis
- NCT number
- NCT06095271
What you commit to
- Study type: Interventional
- Participants enrolled: 920
- From 5 Feb 2023 to the primary completion date, Nov 2026
- 8 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Inclusion or planned inclusion in another clinical trial that determines the drug therapy for MS for the purpose of research as these patients are most likely not following the SMSC usual care.
Who the study is looking for
- Diagnosis of RRMS according to the most recent McDonald criteria (2017) for at least one year
- Have already consented to take part in the SMSC
- Age 18 years old or older
- Able and willing to consent
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (8)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Kantonsspital Aarau Coordinator of this site? Confirm its status | Aarau | Switzerland | Unknown status |
| University Hospital Basel Coordinator of this site? Confirm its status | Basel | Switzerland | Unknown status |
| Inselspital Bern Coordinator of this site? Confirm its status | Bern | Switzerland | Unknown status |
| Hôpitaux universitaires de Genève Coordinator of this site? Confirm its status | Geneva | Switzerland | Unknown status |
| Centre Hospitalier Universitaire Vaudois Coordinator of this site? Confirm its status | Lausanne | Switzerland | Unknown status |
| Ospedale Regionale di Lugano, Sede Civico Coordinator of this site? Confirm its status | Lugano | Switzerland | Unknown status |
| Kantonsspital St. Gallen Coordinator of this site? Confirm its status | Sankt Gallen | Switzerland | Unknown status |
| Universitätsspital Zürich Coordinator of this site? Confirm its status | Zurich | Switzerland | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.