NCT06096675Recruiting
CAPACITY (Cardiac Amyloidosis and Physical ACtivITY) Study
Pilot Study Evaluating Supervised Cardiac Rehabilitation in Patients With Cardiac Amyloidosis
Source: ClinicalTrials.gov · Last updated 21 Jul 2026
Brief summary (registry, in English)
Exercise training in patients with heart failure and preserved ejection fraction (HFpEF) has been associated with an improvement in cardiorespiratory fitness and quality of life.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 50 (estimated)
- First submitted
- 17 Oct 2023
- Start date
- 22 Jan 2024
- Primary completion date
- Dec 2027
- Lead sponsor
- Wake Forest University Health Sciences
- Diseases
- Amyloidosis, Heart failure
- NCT number
- NCT06096675
What you commit to
- Study type: Interventional
- Planned participants: 50
- From 22 Jan 2024 to the primary completion date, Dec 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Gait instability or history of prior falls
Other illness
- NYHA Class IV Heart Failure
- Pulmonary disease requiring home oxygen
- In the opinion of the Principal Investigator, have a clinically significant comorbid disease that is likely to affect the ability of the patient to complete the trial, interfere with their ability with measurement of self-reported outcomes.
Other
- Inability to provide informed consent
- Inability to commit to in-person supervised exercise sessions for three one-hour sessions a week for 12 weeks
Who the study is looking for
- Age \> 18
- New York Heart Association (NYHA) Class I-III Heart Failure
- Able to Exercise
- On stable treatment for their cardiac amyloidosis or under active surveillance
- Life expectancy of at least 6 months
- Ability to understand and the willingness to sign a written informed consent document in English, and the willingness/ability to comply with the protocol activities
- Participant must be able and willing to follow the cardiac rehabilitation activities
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Sanger Heart and Vascular Institute Coordinator of this site? Confirm its status | Charlotte | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.