NCT06102252Completed
Combination Chemotherapy of Paclitaxel and Carboplatin With or Without Anthracycline as Aneo Adjuvant Treatment in Advanced Endometrial Carcinoma
Source: ClinicalTrials.gov · Last updated 22 May 2026
Brief summary (registry, in English)
Endometrial cancer, the most common gynecologic cancer worldwide, is steadily increasing in developed countries.The early-stage forms of endometrial cancer are usually highly curable by surgical treatment alone, whereas advanced stages require adjuvant interdictions such as radiotherapy and chemotherapy. Platinum and anthracycline drugs have long been used as standard adjuvant chemotherapy drugs for advanced and recurrent endometrial carcinomas. In one study, the standard combination adjuvant treatment with AP was found to be more effective as an adjuvant therapy than whole abdominal irradiation
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 60 (actual)
- First submitted
- 22 Oct 2023
- Start date
- 15 Aug 2024
- Primary completion date
- 1 Nov 2025
- Lead sponsor
- Sohag University
- Diseases
- Endometrial cancer
- NCT number
- NCT06102252
What you commit to
- Study type: Interventional
- Participants enrolled: 60
- From 15 Aug 2024 to the primary completion date, 1 Nov 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- • Pt has received prior radiation or chemotherapy.
- Pt with sarcomatous component
- Metastatic endometrial carcinoma
- Other malignancy
- Unfit patient for chemotherapy
Who the study is looking for
- more than 20 years old.
- Any histological type of endometrial carcinoma
- Stage III, IV
- Stage one I or II with one or more of the following factors:
- Histologic grade 3 endometroid carcinoma with myometrial invasion still within half of the myometrium
- histological grade 1,2 endometroid carcinomas with invasion of over half of myometrium
- cervical stromal invasion
- vascular invasion; or
- serous carcinoma, clear cell carcinoma, or undifferentiated carcinoma
- performance status 0-2
- adequate function of all major organs
Age in the registry: 20 years to 70 years · Sex: Female · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Sohag University Hospital Coordinator of this site? Confirm its status | Sohag | Egypt | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.