NCT06102915Completed
Rocuronium vs Cis-atracurium: Do Rocuronium Still 'ROCKS' In Coronary Artery Bypass Grafting
Source: ClinicalTrials.gov · Last updated 28 Nov 2023
Brief summary (registry, in English)
The current trend in most cardiac surgeries was to use rocuronium as it provides faster recovery in train-of-four ratio compared to other aminosteroid non-depolarising neuromuscular blocker. However, as most cardiac centres' standard of care does not perform any neuromuscular monitoring nor antagonism of neuromuscular blockade effect, residual neuromuscular blockade could potentially be the key to delayed extubation. As such, Cis-atracurium's organ-independent Hofmann elimination could be in favour.
- Status (registry)
- Completed
- Study type
- Observational
- Enrollment
- 289 (actual)
- First submitted
- 22 Oct 2023
- Start date
- 1 Aug 2023
- Primary completion date
- 23 Nov 2023
- Lead sponsor
- Institut Jantung Negara
- Diseases
- Coronary artery disease
- NCT number
- NCT06102915
What you commit to
- Study type: Observational
- Participants enrolled: 289
- From 1 Aug 2023 to the primary completion date, 23 Nov 2023
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Recent history of pulmonary infection four weeks before surgery
Other
- Exposed to both neuromuscular blockade within 24 hours perioperatively
- Patients intubated or on tracheostomies pre-operatively
- Any missing or incomplete data
Who the study is looking for
- All patients that undergo general anaesthesia for CABG surgery requiring neuromuscular blockade of either rocuronium or cis-atracurium
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Institut Jantung Negara Coordinator of this site? Confirm its status | Kuala Lumpur | Malaysia | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.