NCT06105164Recruiting
Validation of a Novel Cerebellar-striatal Satiety Circuit in Humans
Source: ClinicalTrials.gov · Last updated 5 Dec 2025
Brief summary (registry, in English)
This study uses a noninvasive technique called transcranial magnetic stimulation (TMS) to study satiety in healthy individuals. TMS is a noninvasive way of stimulating the brain, using a magnetic field to change activity in the brain. The magnetic field is produced by a coil that is held next to the scalp. In this study, the investigators will be stimulating the brain to learn more about the role of the cerebellum in satiety.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 150 (estimated)
- First submitted
- 19 Oct 2023
- Start date
- 5 Dec 2024
- Primary completion date
- Aug 2029
- Lead sponsor
- Brigham and Women's Hospital
- Diseases
- Obesity
- NCT number
- NCT06105164
What you commit to
- Study type: Interventional
- Planned participants: 150
- From 5 Dec 2024 to the primary completion date, Aug 2029
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- On a restricted diet and/or taking weight loss medication(s)
Other illness
- Current and/or past medical conditions
- Current and/or past eating disorder
- History of bariatric surgery
- Recent history of illicit recreational drug abuse
- Conditions that might result in increased risks of side effects or complications from TMS or MRI
Other
- Weight fluctuation \>3% in past 3 months
- Current nicotine use
- Intellectual disability
Who the study is looking for
- Healthy individuals aged 18 to 65
- BMI of 20-35.0 kg/m2
- Normal or corrected-to-normal vision
- Good general health
- Ability to understand and willingness to sign written informed consent document
Age in the registry: 18 years to 65 years · Sex: All · Accepts healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| McLean Hospital Coordinator of this site? Confirm its status | Belmont | United States | Recruiting |
| Brigham and Women's Hospital Coordinator of this site? Confirm its status | Boston | United States | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.