NCT06111833Recruiting
Optimized Diagnosis and Precision Medicine of MODY
Optimized Diagnosis and Precision Medicine of MODY (Maturity-Onset Diabetes of the Young)
Source: ClinicalTrials.gov · Last updated 1 Nov 2023 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
The goal of this observation is to establish a complete registry for the clinical manifestations, environment, genetic, and other related gene variation information of young-onset diabetic patients. Moreover, according to the physiological and pathological mechanisms of different genes, the impact on the clinical characteristics of diabetes, the therapeutic response to drugs, and the impact on complications will be analyzed. The main questions are: 1. The distribution of different types of MODY 2. The phenotypes and clinical characteristics of different types of MODY 3. Response to antidiabetic drugs among different types of MODY Once the participant is enrolled, their questionnaire information (including disease course and development, health history, family history, drug history, etc.), medication, outpatient/inpatient medical history, etc. will be collected and logged in. Blood and urine samples will also be collected for biochemical tests genetic testing, etc. At the same time, the investigators will conduct a continuous follow-up on a regular basis (3 months, 6 months, 12 months, 24 months, and 5 years after the study subject is enrolled). Young-onset type 2 diabetes will be compared to see the difference in clinical presentations and responses to antidiabetic drugs.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 1500 (estimated)
- First submitted
- 4 Oct 2023
- Start date
- 22 May 2023
- Primary completion date
- 21 Apr 2028
- Lead sponsor
- Taichung Veterans General Hospital
- Diseases
- Type 2 diabetes
- NCT number
- NCT06111833
What you commit to
- Study type: Observational
- Planned participants: 1500
- From 22 May 2023 to the primary completion date, 21 Apr 2028
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Cases that have received a blood transfusion within the last six months.
Other illness
- Confirmed Diagnosed with type 1 diabetes.
- Patients who have undergone chemotherapy or radiation therapy for cancer within the last 12 months.
Age
- Under 18 years of age.
Other
- Unable to personally provide informed consent.
- Patients with unrelieved leukemia.
- Unwilling or unable to continue treatment follow-up at this hospital.
Who the study is looking for
- Case Group Diagnosis of diabetes at or before 25 years of age. BMI (Body Mass Index) of 25 kg/m² or lower. Having at least one parent diagnosed with type 2 diabetes.
- Family Group Direct blood relatives of the case group, including brothers and sisters of the case group, who have contacted the research team through the subjects.
- Expressing willingness to participate in this study after granting informed consent.
- Control Group Diagnosis of diabetes occurred at or before the age of 40, and the individual lacks typical MODY (Maturity-Onset Diabetes of the Young) characteristics.
- At least one parent has been diagnosed with type 2 diabetes.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Taichung Veterans General Hospital Coordinator of this site? Confirm its status | Taichung | Taiwan | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.