NCT06115122Recruiting
PEPPI Study: Identification of Women at Risk for Placental Dysfunction
PEPPI Study: Identification of Women at Risk for Placental Dysfunction During the First and Third Trimesters of Pregnancy
Source: ClinicalTrials.gov · Last updated 5 Aug 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
The main purpose of this study is to evaluate Fetal Medicine Foundation's pre-eclampsia risk calculator using maternal characteristics, first trimester serum placental growth factor (PlGF) and mean arterial pressure (MAP) in a Finnish general population. Condition or disease: pre-eclampsia, intrauterine growth restriction, polycystic ovary syndrome
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 3000 (estimated)
- First submitted
- 28 Nov 2022
- Start date
- Feb 2022
- Primary completion date
- Dec 2027
- Lead sponsor
- Oulu University Hospital
- Diseases
- High blood pressure
- NCT number
- NCT06115122
What you commit to
- Study type: Observational
- Planned participants: 3000
- From Feb 2022 to the primary completion date, Dec 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Multiple pregnancy
- Miscarriage/termination of the index pregnancy
- No first trimester blood sampling
- No first or third trimester blood sampling
- No umbilical cord blood sample after baby is born
- Fathers
- Does not understand Finnish
- Children
- No consent from parent(s)
- Mother/father declines participation
- No consent from parent(s)
- No blood samples from mother
- No blood samples from child
Who the study is looking for
- Pregnant (first trimester)
- Understands Finnish
- ≥18 years
- Signed informed consent
- Participates in PEPPI-study (criteria above)
- Blood samples at first and third trimester of pregnancy
- Permits blood sampling from the umbilical cord when the baby is born
- Biological father to the child born for the mother who participated in PEPPI study
- ≥18 years
- Signed informed consent
- Born to mother who participated in PEPPI study
- Signed informed consent from parent(s)
- Signed informed consent from parent(s)
- Mother has blood samples taken at first and third trimester (iron status)
- Child has blood samples taken at birth and at 3 months of age
Criteria the registry did not label
- Mothers
Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| The Wellbeing Services County of North Ostrobothnia Coordinator of this site? Confirm its status | Oulu | Finland | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.