Head Position After Endovascular Therapy

Other illness

• Pre-stroke mRS score\>1 point;
• Any terminal illness with life expectancy less than 6 months;
• Patients with a preexisting neurological or psychiatric disease that would confound the neurological functional evaluations;

Lab values

• Currently in pregnant or lactating or serum beta HCG test is positive on admission;

Other

• Patients with acute occlusions in multiple vascular territories (e.g. bilateral anterior circulation, or anterior/posterior circulation);
• Contraindications to a flat head position;
• Participating in other clinical trials;
• Unlikely to be available for 90-day follow-up.

• Clinical signs consistent with acute ischemic stroke;
• Age ≥ 18 years old;
• Proved anterior circulation large vessel occlusion on digital subtraction angiography (ICA, M1, M2) with/without cervical lesion (tandem);
• NIHSS score ≥ 8 points before endovascular treatment;
• ASPECTS score ≤ 7 points before endovascular treatment;
• Successful vessel recanalization after endovascular treatment (defined as an eTICI score of 2b, 2c, or 3) ；
• The time from onset to randomization ≤ 24 hours (the onset time is defined as the last normal time);
• Written informed consent is obtained from patients and/or their legal representatives.