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NCT06122220Completed

Optic Nerve Sheath Measurement and Angiogenic Factors in Patients With Pre-eclampsia.

Optic Nerve Sheath Measurement and Angiogenic Factors for the Diagnosis of Pre-eclampsia

Source: ClinicalTrials.gov · Last updated 16 Jul 2026

Brief summary (registry, in English)

Hypertensive disorders of pregnancy (HPT) are an important cause of maternal-feto-neonatal morbidity and mortality, being one of the three leading causes of maternal death in our country and in developing countries. The only cure for THE is termination of pregnancy, which ends up being a decision in which gestational age and maternal risks must be balanced. Angiogenic factors have come to occupy an indispensable place in the arsenal of tools that can be used to separate the patient with a high likelihood of complications from those in whom prolongation of pregnancy could represent an important neonatal benefit. Refining the diagnostic capability of this test would further improve maternal-fetal outcomes and the use of optic nerve sheath diameter (ONSD) measurement could make the difference. The purpose of the present study is to correlate the measurement of ONSD with serum angiogenic factor (AF) values in patients with pre-eclampsia and to determine its predictive ability for adverse perinatal outcomes.

Status (registry)
Completed
Study type
Interventional
Enrollment
200 (actual)
First submitted
26 Oct 2023
Start date
15 Aug 2025
Primary completion date
31 Mar 2026
Lead sponsor
Saint Thomas Hospital, Panama
NCT number
NCT06122220

What you commit to

  • Study type: Interventional
  • Participants enrolled: 200
  • From 15 Aug 2025 to the primary completion date, 31 Mar 2026
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Previous cesarean section (3 or more)

Other illness

  • Neurological conditions
  • Chronic renal disease
  • Heart disease

Other

  • Multiple gestation
  • Maternal vasculitis
  • Brain or eye tumors
  • Purpura

Who the study is looking for

  • Pregnant women between 24 and 40 weeks of gestation.

Age in the registry: 18 years to - · Sex: Female · Accepts healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
Saint Thomas Hospital
Coordinator of this site? Confirm its status
Panama CityPanamaUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.