NCT06125795Active, not recruiting
A Study to Assess Change in Functioning and Health Related Quality of Life in Adult Participants With Chronic Lymphocytic Leukemia (CLL) Receiving Oral Treatments in Routine Clinical Practice in Spain
Non-interventional Prospective Descriptive Study to Assess the Impact on Patient´s Well-being of Fixed-time Duration (FTD) and Continuous Oral Regimens for Newly Diagnosed and Relapsed/Refractory (R/R) Chronic Lymphocytic Leukemia (CLL) in Routine Clinical Practice in Spain
Source: ClinicalTrials.gov · Last updated 1 May 2026
Brief summary (registry, in English)
Chronic lymphocytic leukemia (CLL) is the most common leukemia in the Western world. Since in most cases CLL remains an incurable disease, the goals of therapy are to improve quality of life and to prolong survival. This study will evaluate the participant's related outcomes and experience of CLL in adult participants who are treated in the Spain. Study participants will receive oral treatments for CLL as prescribed by their study doctor in accordance with approved local label. Adult participants prescribed various treatments will be enrolled. Around 132 participants will be enrolled in the study in sites in Spain. Participants will receive oral treatments for CLL according to the approved local label. The overall study duration will be 18 months. There is expected to be no additional burden for participants in this trial. All study visits will occur during routine clinical practice.
- Status (registry)
- Active, not recruiting
- Study type
- Observational
- Enrollment
- 146 (actual)
- First submitted
- 24 Oct 2023
- Start date
- 6 Nov 2023
- Primary completion date
- Jul 2026
- Lead sponsor
- AbbVie
- Diseases
- Chronic lymphocytic leukaemia
- NCT number
- NCT06125795
What you commit to
- Study type: Observational
- Participants enrolled: 146
- From 6 Nov 2023 to the primary completion date, Jul 2026
- 25 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Currently receiving any chemotherapy or chemoimmunotherapy.
Lab values
- Any serious medical condition or abnormality in clinical laboratory tests that, in the investigator's judgment, precludes the participant's safe participation in and completion of the study.
Other
- Transformation of CLL to aggressive non-Hodgkin's lymphoma (NHL) (Richter's transformation or pro-lymphocytic leukaemia).
- Currently participating in interventional research (not including non-interventional study, post-marketing observational study, or registry participation).
Who the study is looking for
- Have documented chronic lymphocytic leukemia (CLL) according to International Workshop on Chronic Lymphocytic Leukemia (iwCLL) criteria.
- Under oral treatment for CLL, either first-line or relapsed/refractory (R/R) therapy.
- Treatment for CLL started 9 months (+/- 4 weeks) before inclusion for first-line therapy or 21 months (+/- 4 weeks) before inclusion for R/R, under authorized conditions.
- In the opinion of the investigator, cognitive ability to understand and answer the questionnaires specified in the study protocol.
- Able to comply with the study protocol in the investigator's judgment.
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (25)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Hospital de Sant Joan Despi Moises Broggi /ID# 262284 Coordinator of this site? Confirm its status | Barcelona | Spain | Unknown status |
| Hospital Universitario Reina Sofia /ID# 271507 Coordinator of this site? Confirm its status | Córdoba | Spain | Unknown status |
| Hospital Clinico Universitario Virgen de la Arrixaca /ID# 262173 Coordinator of this site? Confirm its status | El Palmar | Spain | Unknown status |
| Hospital Universitario de Fuenlabrada /ID# 258275 Coordinator of this site? Confirm its status | Fuenlabrada | Spain | Unknown status |
| Hospital Universitario de Galdakao /ID# 258264 Coordinator of this site? Confirm its status | Galdakao | Spain | Unknown status |
| Hospital de Cabuenes /ID# 263307 Coordinator of this site? Confirm its status | Gijón | Spain | Unknown status |
| Hospital Universitario Virgen de las Nieves /ID# 258280 Coordinator of this site? Confirm its status | Granada | Spain | Unknown status |
| Hospital Jerez De La Frontera /ID# 258282 Coordinator of this site? Confirm its status | Jerez de la Frontera | Spain | Unknown status |
| Hospital Comarcal de Laredo /ID# 258262 Coordinator of this site? Confirm its status | Laredo | Spain | Unknown status |
| Hospital Universitario Dr. Negrin /ID# 258285 Coordinator of this site? Confirm its status | Las Palmas de Gran Canaria | Spain | Unknown status |
| Hospital Universitario de León /ID# 271526 Coordinator of this site? Confirm its status | León | Spain | Unknown status |
| Hospital Lucus Augusti /ID# 271542 Coordinator of this site? Confirm its status | Lugo | Spain | Unknown status |
| Hospital Universitario La Paz /ID# 258270 Coordinator of this site? Confirm its status | Madrid | Spain | Unknown status |
| Hospital General Universitario Gregorio Maranon /ID# 258273 Coordinator of this site? Confirm its status | Madrid | Spain | Unknown status |
| Hospital Universitario Fundacion Jimenez Diaz /ID# 258269 Coordinator of this site? Confirm its status | Madrid | Spain | Unknown status |
| Hospital Universitario 12 de Octubre /ID# 258271 Coordinator of this site? Confirm its status | Madrid | Spain | Unknown status |
| Hospital Universitario de La Princesa /ID# 271506 Coordinator of this site? Confirm its status | Madrid | Spain | Unknown status |
| Sant Joan de Deu de Manresa /ID# 258266 Coordinator of this site? Confirm its status | Manresa | Spain | Unknown status |
| Hospital General Universitario Morales Meseguer /ID# 258284 Coordinator of this site? Confirm its status | Murcia | Spain | Unknown status |
| Hospital Universitario Central de Asturias /ID# 271508 Coordinator of this site? Confirm its status | Oviedo | Spain | Unknown status |
| Hospital Universitario Marques de Valdecilla /ID# 258261 Coordinator of this site? Confirm its status | Santander | Spain | Unknown status |
| Hospital Universitario Virgen Macarena /ID# 258279 Coordinator of this site? Confirm its status | Seville | Spain | Unknown status |
| Hospital Universitari Mútua Terrassa /ID# 258267 Coordinator of this site? Confirm its status | Terrassa | Spain | Unknown status |
| Hospital Meixoeiro (CHUVI) /ID# 258286 Coordinator of this site? Confirm its status | Vigo | Spain | Unknown status |
| HUA - Txagorritxu /ID# 258263 Coordinator of this site? Confirm its status | Vitoria-Gasteiz | Spain | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.