NCT06129253Recruiting
Global Burden Estimation of Human Papillomavirus (GLOBE-HPV)
Source: ClinicalTrials.gov · Last updated 16 Jul 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
This study is a multi-country and multi-site project to estimate the point-prevalence of high-risk (HR) HPV genotype infections among representative samples of girls and women aged 9-50 years, and among specific sub-populations to estimate the incidence of persistent HPV infection among sexually active young women. The data to fulfill the objectives will be collected through a series of Cross-Sectional Surveys (CSS) and Longitudinal Studies (LS) in all 8 countries 3 South Asian countries including Bangladesh, Pakistan, Nepal and 5 sub-Saharan African countries including Sierra Leone, Tanzania, Ghana, Zambia and DR Congo. Qualitative sub-studies (QS) will be conducted in selected countries and populations following the CSS to further understand and unpack risk factors for HPV infection as well as to explore how gender-related dynamics including perceptions of gender norms and stigma, influence HPV burden and/or create barriers that shape girls/women access to and uptake of HPV prevention, screening, and treatment services. Specific study protocols and corresponding ethical applications for the qualitative sub-studies will be developed separately.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 29750 (estimated)
- First submitted
- 17 Oct 2023
- Start date
- 23 Nov 2023
- Primary completion date
- 31 Dec 2027
- Lead sponsor
- International Vaccine Institute
- Diseases
- Cervical cancer, Childhood cancers
- NCT number
- NCT06129253
What you commit to
- Study type: Observational
- Planned participants: 29750
- From 23 Nov 2023 to the primary completion date, 31 Dec 2027
- 8 sites in 8 countries
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- A medical condition or other reason, not directly related to HPV infection or HPV-related diseases, in the opinion of the investigator, precludes enrolment in the study.
Other
- Decline consent to participate any activity of the study.
Who the study is looking for
- 9 to 50 years old (for urban and rural CSSs) at the time of enrollment.
- Resident in the selected community for at least the past 3 months (with the exception of pastoralists, refugees, and commercial sex workers).
- Able to understand the purpose of the study and study procedures.
- If aged 18 years or older or legally considered an emancipated minor, able and willing to provide consent to participate in the study including sample collection.
- If aged \<18 years (and not considered an emancipated minor), supported in their participation by a parent or guardian who is able and willing to provide consent, and
- If aged \<18 years (and not considered an emancipated minor), able and willing to provide assent to participate in the study.
Age in the registry: 9 years to 50 years · Sex: Female · Accepts healthy volunteers
Sites (8)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Diarrhoeal Disease Research, Bangladesh (icddr,b) Coordinator of this site? Confirm its status | Dhaka | Bangladesh | Completed |
| University of Health and Allied Sciences (UHAS) Coordinator of this site? Confirm its status | Ho | Ghana | Completed |
| Dhulikhel Hospital Kathmandu University Hospital (DHKUH) Coordinator of this site? Confirm its status | Dhulikhel | Nepal | Completed |
| Aga Khan University (AKU) Coordinator of this site? Confirm its status | Karachi | Pakistan | Completed |
| College of Medicine and Allied Health Sciences (COMAHS) Coordinator of this site? Confirm its status | Freetown | Sierra Leone | Completed |
| Mwanza Intervention Trial Unit (MITU) Coordinator of this site? Confirm its status | Mwanza | Tanzania | Completed |
| ZAMBART Coordinator of this site? Confirm its status | Lusaka | Zambia | Completed |
| Institut National pour la Recherche Biomedicale (INRB) Coordinator of this site? Confirm its status | Kinshasa | Democratic Republic of the Congo | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.