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NCT06133764Completed

Risk-Adapted Treatment Strategies for Odontogenic Keratocysts: A Long-Term Randomized Clinical Trial Quantifying Recurrence Reduction

Analysis of Odontogenic Keratocyst Treated With Various Modalities Over a 10-year

Source: ClinicalTrials.gov · Last updated 7 Jan 2026

Brief summary (registry, in English)

Background The odontogenic keratocysts (OKCs) have been one of the maxillofacial region's most contentious pathological phenomena. Decompression/marsupialization (D/M), enucleation (E), enucleation + chemical cauterization with Carnoy's solution (E+CS), enucleation + peripheral ostectomy (E + PO), as opposed to enucleation + chemical cauterization with Carnoy's solution + peripheral ostectomy (E + CS + PO), were used during surgery to ensure that no epithelial remnants were left behind. Rationale Through the management of OKC a recurrence could occur, the effectiveness of Decompression/marsupialization (D/M), Enucleation (E), Enucleation+Carnoy's solution chemical cauterization (E+CS), Enucleation+peripheral ostectomy (E+PO), Enucleation+Carnoy's solution chemical cauterization + peripheral ostectomy (E+CS + PO), will be analyzed

Status (registry)
Completed
Study type
Interventional
Enrollment
50 (actual)
First submitted
8 Nov 2023
Start date
24 Feb 2023
Primary completion date
30 Jun 2024
Lead sponsor
Qassim University
NCT number
NCT06133764

What you commit to

  • Study type: Interventional
  • Participants enrolled: 50
  • From 24 Feb 2023 to the primary completion date, 30 Jun 2024
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Prior treatment

  • Cases treated with resection

Other

  • Cases showed neoplastic transformation in their pathology
  • Cyst Like lesions

Who the study is looking for

  • All odontogenic keratocysts that are treated by the following surgical treatment modalities:
    • Enucleation followed by peripheral ostectomy and Carnoy's solution
    • Decompression/ marsupialization
    • Enucleation
    • Enucleation and Carnoy's solution
    • Enucleation and Peripheral Ostectomy
  • Follow-up period 10 years

Age in the registry: 10 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
College of Dentistry, Qassim University
Coordinator of this site? Confirm its status
BuraidahSaudi ArabiaUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.