Fact CheckerSign in

NCT06133907Active, not recruiting

Investigation of the Frequency of Hereditary Hyper Alpha-tryptasemia in Patients With Elevated Basal Tryptasemia

Investigation of the Frequency of Hereditary Hyper Alpha-tryptasemia in Patients With Elevated Basal Tryptasemia (Protocol HaT)

Source: ClinicalTrials.gov · Last updated 20 May 2026

Brief summary (registry, in English)

The aim of the study is to assess the number of patients with elevated blood tryptase for whom this elevation could be linked to a hereditary alpha-tryptase secretion abnormality or hyper-alpha-tryptasemia. This information will enable to better optimize the management and follow-up of patients who have experienced hypersensitivity reactions and have elevated basal blood tryptase levels. The patients will be offered the opportunity to take part in the study. If they consent to participate, they will be tested for hereditary hyper-alpha-tryptasemia. A blood sampling will be performed in the center. A few weeks after, the patient will be informed about the blood sample result during a medical consultation organized in the center.

Status (registry)
Active, not recruiting
Study type
Interventional
Enrollment
100 (estimated)
First submitted
9 Nov 2023
Start date
5 Dec 2023
Primary completion date
5 Dec 2025
Lead sponsor
Centre Hospitalier Universitaire de Nice
NCT number
NCT06133907

What you commit to

  • Study type: Interventional
  • Planned participants: 100
  • From 5 Dec 2023 to the primary completion date, 5 Dec 2025
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other

  • High tryptasemia (≥ 8ng/ml) synchronous with anaphylactic reaction and unconfirmed basally
  • Known diagnosis of systemic mastocytosis

Who the study is looking for

  • Patients who came in the pneumoallergology department of the CHU de Nice since January 2014 for an allergological workup
  • Patients who have received at least one basal tryptase assay, according to recommendations
  • informed consent signature

Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
CHU de Nice - Hôpital de Pasteur
Coordinator of this site? Confirm its status
NiceFranceUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.