NCT06136871Completed
Cognitive Rehabilitation in Post-COVID-19 Syndrome
Cognitive Strategy Training in Post-COVID-19 Syndrome: A Feasibility Trial
Source: ClinicalTrials.gov · Last updated 13 Mar 2026
Brief summary (registry, in English)
The first aim of this study is to determine the feasibility of delivering CO-OP remotely to individuals experiencing cognitive impairments that limit everyday activities in post-COVID-19 syndrome (PCS). The second aim of this study is to assess the effect of CO-OP on activity performance, subjective and objective cognition, and quality of life in a sample of individuals with PCS. The research team hypothesizes that effect size estimations will indicate that CO-OP will have a greater positive effect, compared to an inactive control group, on activity performance, subjective and objective cognition, and quality of life in a sample of individuals who self-report PCS and cognitive impairment.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 65 (actual)
- First submitted
- 14 Nov 2023
- Start date
- 1 Feb 2024
- Primary completion date
- 30 Jun 2025
- Lead sponsor
- University of Missouri-Columbia
- Diseases
- Long COVID and ME/CFS
- NCT number
- NCT06136871
What you commit to
- Study type: Interventional
- Participants enrolled: 65
- From 1 Feb 2024 to the primary completion date, 30 Jun 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- diagnosis of severe neurological or psychiatric condition(s)
- dementia symptoms as indicated by a score of \<23 on the Montreal Cognitive Assessment (MoCA)
- prior cancer treatment
Other
- untreated sleep apnea (≥5 on the STOPBANG)
- severe depressive symptoms (\>21 on the Patient Health Questionnaire-9)
Who the study is looking for
- self-reported cognitive symptoms persisting for at least 6 weeks following COVID-19 infection (Cognitive Failures Questionnaire (CFQ) score \>43)
- self-identified activity performance goals per the Canadian Occupational Performance Measure (COPM)
- documented prior diagnosis of COVID-19
- read, write, and speak English fluently
- ability to provide valid informed electronic consent
Age in the registry: 18 years to 60 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| University of Missouri Department of Occupational Therapy Coordinator of this site? Confirm its status | Columbia | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.