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NCT06136871Completed

Cognitive Rehabilitation in Post-COVID-19 Syndrome

Cognitive Strategy Training in Post-COVID-19 Syndrome: A Feasibility Trial

Source: ClinicalTrials.gov · Last updated 13 Mar 2026

Brief summary (registry, in English)

The first aim of this study is to determine the feasibility of delivering CO-OP remotely to individuals experiencing cognitive impairments that limit everyday activities in post-COVID-19 syndrome (PCS). The second aim of this study is to assess the effect of CO-OP on activity performance, subjective and objective cognition, and quality of life in a sample of individuals with PCS. The research team hypothesizes that effect size estimations will indicate that CO-OP will have a greater positive effect, compared to an inactive control group, on activity performance, subjective and objective cognition, and quality of life in a sample of individuals who self-report PCS and cognitive impairment.

Status (registry)
Completed
Study type
Interventional
Enrollment
65 (actual)
First submitted
14 Nov 2023
Start date
1 Feb 2024
Primary completion date
30 Jun 2025
Lead sponsor
University of Missouri-Columbia
NCT number
NCT06136871

What you commit to

  • Study type: Interventional
  • Participants enrolled: 65
  • From 1 Feb 2024 to the primary completion date, 30 Jun 2025
  • 1 site in 1 country
  • Visits and tests: ask the trial team, the registry does not list them

Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.

Who cannot take part

Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.

Other illness

  • diagnosis of severe neurological or psychiatric condition(s)
  • dementia symptoms as indicated by a score of \<23 on the Montreal Cognitive Assessment (MoCA)
  • prior cancer treatment

Other

  • untreated sleep apnea (≥5 on the STOPBANG)
  • severe depressive symptoms (\>21 on the Patient Health Questionnaire-9)

Who the study is looking for

  • self-reported cognitive symptoms persisting for at least 6 weeks following COVID-19 infection (Cognitive Failures Questionnaire (CFQ) score \>43)
  • self-identified activity performance goals per the Canadian Occupational Performance Measure (COPM)
  • documented prior diagnosis of COVID-19
  • read, write, and speak English fluently
  • ability to provide valid informed electronic consent

Age in the registry: 18 years to 60 years · Sex: All · Does not accept healthy volunteers

Full criteria on ClinicalTrials.gov

Sites (1)

Sites in registry order. Pick your city on the disease page to sort them by distance.

SiteCityCountrySite status
University of Missouri Department of Occupational Therapy
Coordinator of this site? Confirm its status
ColumbiaUnited StatesUnknown status

This page is information, not medical advice. Discuss any trial with your doctor.