NCT06140719Withdrawn
xPedite: A Study to Expedite DIPG and DMG Research
A Retrospective and Prospective Observational Sub-Study for Diffuse Midline Glioma and Diffuse Intrinsic Pontine Glioma
Source: ClinicalTrials.gov · Last updated 2 Nov 2026
Reason given: Protocol termination
Brief summary (registry, in English)
This study will gather data from new and existing patients with patient medical records, and patient/family/caregiver reported information to establish a clear natural history of disease suitable to serve as an external, contemporary or historical control arm for future therapeutic development programs of drugs, devices, or biologic interventions in DMG or DIPG.
- Status (registry)
- Withdrawn
- Study type
- Observational
- Enrollment
- 0 (actual)
- First submitted
- 7 Nov 2023
- Start date
- 1 Nov 2023
- Primary completion date
- 14 Oct 2024
- Lead sponsor
- xCures
- Diseases
- Childhood cancers
- NCT number
- NCT06140719
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Patient or legally-authorized representative is unable to provide informed consent.
- Patient or caregiver is unable to complete the PRO and ClinRO by an electronic platform.
Who the study is looking for
- Diagnosis of diffuse midline glioma according to the WHO 2021 Classification of Tumors of the Central Nervous System diagnostic criteria including diffuse intrinsic pontine glioma (DIPG). In the absence of a pathologically confirmed diagnosis, a grade IV glioma involving the thalamus, hypothalamus, brainstem, cerebellum, midbrain, or spinal cord, or with a pontine epicenter and diffuse involvement of the pons.
- Patients with any performance status, comorbidity or disease severity are eligible
- Patients or their legally-authorized representative must be willing and able to provide electronic, informed consent (and assent, if applicable)
- Informed consent obtained for the XCELSIOR longitudinal outcomes registry (NCT03793088).
- Patients must be a resident of or receiving care within the United States or US territories.
Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| xCures, Inc. | Los Altos | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.