NCT06141668Completed
Optimal Stimulation Parameters to Disrupt Epileptiform Activity
Optimal Stimulation Parameters for Spike-ripple Disruption in Patients Undergoing Invasive Monitoring
Source: ClinicalTrials.gov · Last updated 2 Sept 2026
Brief summary (registry, in English)
Open-loop electrical stimulation has been found to reduce spike activity and seizures, but determining the optimal parameters to achieve these effects requires a brute force trial-and-error approach that relies on subjective physician discretion. We compared the performance of stimulation parameters identified in rodent models to the recommended parameters for neuromodulation used in clinical practice.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 16 (actual)
- First submitted
- 15 Nov 2023
- Start date
- 13 Jun 2023
- Primary completion date
- 30 Jun 2025
- Lead sponsor
- Massachusetts General Hospital
- Diseases
- Epilepsy
- NCT number
- NCT06141668
What you commit to
- Study type: Interventional
- Participants enrolled: 16
- From 13 Jun 2023 to the primary completion date, 30 Jun 2025
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Baseline spike ripple rate \< 0.5/min.
- Did not complete 3 hours of stimulation.
Who the study is looking for
- Undergoing intracranial EEG investigation at Massachusetts General Hospital during presurgical epilepsy evaluation.
- Consented for stimulation experiment.
Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Massachusetts General Hospital Coordinator of this site? Confirm its status | Boston | United States | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.