NCT06141772Completed
Kinetics of Circulating Tumor DNA in Lymphoma Treated by Immuno-chemotherapy
Prospective Study of Circulating Tumor DNA Kinetics Post R-CHOP Type Treatment of Diffuse Large B Cell Lymphoma
Source: ClinicalTrials.gov · Last updated 2 Jan 2026
Brief summary (registry, in English)
The purpose of this study is to determine the kinetics of circulating tumor DNA (ctDNA) in the hours following initial administration of immuno-chemotherapy to patients with diffuse large B cell lymphoma (DLBCL). Modelizing the short-term kinetics of ctDNA would help to determine the optimal time-point for ctDNA follow-up. The investigators hypothesize that the greater ctDNA release at this time-point compared to baseline might lead lead to the detection of novel variants compared to baseline.
- Status (registry)
- Completed
- Study type
- Interventional
- Enrollment
- 24 (actual)
- First submitted
- 17 Oct 2023
- Start date
- 21 Dec 2023
- Primary completion date
- 4 Nov 2024
- Lead sponsor
- Centre Henri Becquerel
- Diseases
- Diffuse large B-cell lymphoma
- NCT number
- NCT06141772
What you commit to
- Study type: Interventional
- Participants enrolled: 24
- From 21 Dec 2023 to the primary completion date, 4 Nov 2024
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Histology other than Diffuse Large B Cell
- Patient under guardianship or curatorship
- Incapacity to understand the study or conform to the constraints of the study (language barrier, psychological barrier, geographic barrier…)
Who the study is looking for
- 18 years or older
- Diffuse Large B Cell Lymphoma
- TEP-TDM at diagnosis
- Inform Consent form signed
- Performance status 0 or 1
- Hospitalized on clinician decision for first cycle of R-CHOP or R-miniCHOP
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Save your city in your profile to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Centre Henri Becquerel Coordinator of this site? Confirm its status | Rouen | France | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.