NCT06144476Recruiting
Study of Inflammatory and Physiological Profiles of Healthy and Diseased Lung
Source: ClinicalTrials.gov · Last updated 4 Jun 2026
Brief summary (registry, in English)
There are over 700,000 UK hospital admissions every year with lung disease symptoms. Two of the most common lung diseases contributing to these numbers are asthma and chronic obstructive pulmonary disease (COPD). The immunopathology of these diseases is not fully understood. Matched samples from the respiratory tract and circulation will be used to identify immune patterns throughout the respiratory system to elucidate the immunopathology of airway disease.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 230 (estimated)
- First submitted
- 22 Aug 2023
- Start date
- 8 Feb 2024
- Primary completion date
- 31 Aug 2026
- Lead sponsor
- Guy's and St Thomas' NHS Foundation Trust
- NCT number
- NCT06144476
What you commit to
- Study type: Observational
- Planned participants: 230
- From 8 Feb 2024 to the primary completion date, 31 Aug 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Surgery within the preceding 6 weeks
- Alcohol or recreational drug abuse
Other illness
- Known or suspected current pulmonary tuberculosis, HIV (human immunodeficiency virus), Hepatitis B Virus, Hepatitis C Virus.
- History of psychiatric, medical, or surgical disorders that in the opinion of the chief investigator may interfere with sample collection, undergo a bronchoscopy, or may compromise study completion or data collection
Other
- Participants who are pregnant
- Diagnosis of immunodeficiency requiring treatment
- Unable to provide written informed consent
- Unable to read or write English
- Be considered, in the opinion of the investigator, to be an unsuitable candidate for the study
Who the study is looking for
- Participant is willing and able to give informed consent for participation in the study
- Aged 18 years or above
- Patient: known or suspected airway disease
- Healthy volunteer: considered to be in good health with no significant comorbidity (immune disorder, cancer etc.)
Age in the registry: 18 years to - · Sex: All · Accepts healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Guy's & St Thomas' NHS Foundation Trust Coordinator of this site? Confirm its status | London | United Kingdom | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.