NCT06145841Recruiting
Metagenomic Next-Generation Sequencing Guides Anti-Infection Strategies
Clinical Application of Metagenomic Next-Generation Sequencing-Guided Anti-Infection Strategies in AIDS Patients With Severe Pneumonia and/or Sepsis
Source: ClinicalTrials.gov · Last updated 24 Nov 2023 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
This study aims to observe the effectiveness of clinical application in guiding anti-infection treatments in AIDS patients with severe pneumonia and/or sepsis using Metagenomic Next-Generation Sequencing-based technology in the real world
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 400 (estimated)
- First submitted
- 17 Nov 2023
- Start date
- 23 Oct 2023
- Primary completion date
- 23 Oct 2026
- Lead sponsor
- Guangzhou 8th People's Hospital
- Diseases
- HIV
- NCT number
- NCT06145841
What you commit to
- Study type: Observational
- Planned participants: 400
- From 23 Oct 2023 to the primary completion date, 23 Oct 2026
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- Concurrent AIDS-related or unrelated tumors;
- Alcohol abuse or drug use;
Other illness
- Coexisting central nervous system lesions, severe liver disease, or cirrhosis;
- Severe underlying diseases of the heart, lungs, liver, kidneys, etc.;
- The researcher believes that the overall condition of the subject affects the evaluation and completion of the trial.
Other
- Women who are pregnant or breastfeeding;
Who the study is looking for
- Confirmed HIV infection;
- Progression to AIDS stage: CD4+ count \<200 cells/ul and/or occurrence of AIDS opportunistic infections;
- Age between 18 and 65 years;
- Meeting the diagnosis of severe pneumonia or septic shock:
- The criteria for severe pneumonia diagnosis refer to the 2021 ATS (American Thoracic Society) and IDSA (Infectious Diseases Society of America) guidelines for the treatment of community-acquired pneumonia;
- The criteria for septic shock refer to the Chinese Society of Critical Care Medicine's "Chinese Guidelines for the Emergency Treatment of Sepsis/Septic Shock (2018).
Age in the registry: 18 years to 65 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Linghua Li Coordinator of this site? Confirm its status | Guangzhou | China | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.