NCT06148077Recruiting
Manual Therapy on Oral Opening, Swallow Function and Upper Quarter Mobility on Head and Neck Cancer Survivors
Effects of Manual Therapy on Oral Opening, Swallow Function, and Upper Quarter Mobility in Chilean Survivors of Head and Neck Cancer: A Study Protocol for a Controlled, Randomized Study (MATEO Study, MAnual ThErapy for Oral Opening).
Source: ClinicalTrials.gov · Last updated 30 May 2025 · Not updated for over 12 months - ask the site whether it is still open
Brief summary (registry, in English)
Trismus has been reported as the second most common comorbidity in survivors of head and neck cancer (HNC). It is mainly associated with post-radiotherapy subcutaneous fibrosis, muscular atrophy, damage to neurological structures in the neck, or a combination of all, affecting masticatory musculature. In addition to this, the loss of flexibility and strength in the shoulder has also been shown to be related to deficits in the function and quality of life of these patients. The goal of this clinical trial is to determinate the effectiveness and safety of Manual Therapy (MT) on Oral Opening, Swallow Function, as well as the mobility of the upper quarter, the strength of cervical musculature, pain, functionality, and the perception of quality of life in head and neck cancer survivors. Participants will be assigned randomly to the study groups: a) manual therapy program and control motor exercises and b) motor control exercises (usual care). The assessment refers to a baseline form (at the beginning of the study), at 6 weeks and at 6 weeks of patient follow-up.
- Status (registry)
- Recruiting
- Study type
- Interventional
- Enrollment
- 70 (estimated)
- First submitted
- 17 Nov 2023
- Start date
- 25 Sept 2024
- Primary completion date
- 1 Oct 2025
- Lead sponsor
- Universidad de La Frontera
- Diseases
- Head and neck cancer
- NCT number
- NCT06148077
What you commit to
- Study type: Interventional
- Planned participants: 70
- From 25 Sept 2024 to the primary completion date, 1 Oct 2025
- 2 sites in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Prior treatment
- sequelae of previous stroke
Other illness
- metastasis or active cancer
Other
- structural instability and/or osteoporosis of the cervical spine, spondylosis, cervical herniated discs
- active osteoradionecrosis or open wounds (fistulas, soft tissue necrosis) in the anatomical treatment area
- tracheostomized individuals
- refuse to participate.
Who the study is looking for
- individuals with HNC
- individuals over 18 years of age
- individuals who have undergone oncological surgery of the head and neck and/or radiotherapy
- having finished oncological medical treatment between 3 and 36 months before inclusion
- having a medical diagnosis of trismus and/or TMD and/or cervical or shoulder dysfunction
- Spanish native speakers
Age in the registry: 18 years to - · Sex: All · Does not accept healthy volunteers
Sites (2)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Universidad de La Frontera Coordinator of this site? Confirm its status | Temuco | Chile | Recruiting |
| Barbara Burgos Mansilla Coordinator of this site? Confirm its status | Temuco | Chile | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.